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    SNRK2.3 sucrose nonfermenting 1(SNF1)-related protein kinase 2.3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836822, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SNRK2.3
    Official Full Name
    sucrose nonfermenting 1(SNF1)-related protein kinase 2.3
    Primary source
    TAIR:AT5G66880
    Locus tag
    AT5G66880
    See related
    Araport:AT5G66880
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    SNRK2-3; SRK2I; SUCROSE NONFERMENTING 1 (SNF1)-RELATED PROTEIN KINASE 2-3; sucrose nonfermenting 1(SNF1)-related protein kinase 2.3
    Summary
    encodes a member of SNF1-related protein kinases (SnRK2) whose activity is activated by ionic (salt) and non-ionic (mannitol) osmotic stress. Enzyme involved in the ABA signaling during seed germination, dormancy and seedling growth.
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    Genomic context

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    See SNRK2.3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Sequence:
    Chromosome: 5; NC_003076.8 (26710302..26712971)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain-containing protein Neighboring gene ASYMMETRIC LEAVES 2-like 1 Neighboring gene ncRNA Neighboring gene Leucine-rich repeat (LRR) family protein Neighboring gene Disease resistance protein (CC-NBS-LRR class) family Neighboring gene Disease resistance protein (CC-NBS-LRR class) family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of abscisic acid-induced stomatal closure and anion channels by guard cell AAPK kinase. Li J, et al. Science, 2000 Jan 14. PMID 10634783
    2. A dual function of SnRK2 kinases in the regulation of SnRK1 and plant growth. Belda-Palazón B, et al. Nat Plants, 2020 Nov. PMID 33077877
    3. Identification of two protein kinases required for abscisic acid regulation of seed germination, root growth, and gene expression in Arabidopsis. Fujii H, et al. Plant Cell, 2007 Feb. PMID 17307925, Free PMC Article
    4. Nitric oxide suppresses the inhibitory effect of abscisic acid on seed germination by S-nitrosylation of SnRK2 proteins. Wang P, et al. Plant Signal Behav, 2015. PMID 26024299, Free PMC Article
    5. SCFAtPP2-B11 modulates ABA signaling by facilitating SnRK2.3 degradation in Arabidopsis thaliana. Cheng C, et al. PLoS Genet, 2017 Aug. PMID 28787436, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Stomatal regulation: Role of H2S-induced persulfidation in ABA signaling.
      Title: Stomatal regulation: Role of H(2)S-induced persulfidation in ABA signaling.
    2. A dual function of SnRK2 kinases in the regulation of SnRK1 and plant growth.
      Title: A dual function of SnRK2 kinases in the regulation of SnRK1 and plant growth.
    3. -ZIP transcription factors HAT1 can interact with and be phosphorylated by SnRK23 kinase.
      Title: Transcription factor HAT1 is a substrate of SnRK2.3 kinase and negatively regulates ABA synthesis and signaling in Arabidopsis responding to drought.
    4. We show that SnRK2.3 is degradated by 26S proteasome system and abscisic acid (ABA) promotes its degradation. AtPP2-B11 was induced by ABA; knockdown of AtPP2-B11 expression markedly increased ABA sensitivity of plants during seed germination and postgerminative development. These results reveal a novel mechanism through which AtPP2-B11 degrades SnRK2.3 to attenuate ABA signaling and the abiotic stress response.
      Title: SCFAtPP2-B11 modulates ABA signaling by facilitating SnRK2.3 degradation in Arabidopsis thaliana.
    5. Nitric oxide negatively regulates abscissic acid signaling in germination and early seedling growth through S-nitrosylation of SnRK2.2 and SnRK2.3.
      Title: Nitric oxide suppresses the inhibitory effect of abscisic acid on seed germination by S-nitrosylation of SnRK2 proteins.
    6. Data show that the decuple mutant snrk2.1/2/3/4/5/6/7/8/9/10 grew poorly under hyperosmotic stress conditions but was similar to the wild type in culture media in the absence of osmotic stress.
      Title: Arabidopsis decuple mutant reveals the importance of SnRK2 kinases in osmotic stress responses in vivo.
    7. SRK2D, SRK2E and SRK2I protein kinases involved in ABA signaling are essential for the control of seed development and dormancy.
      Title: Three Arabidopsis SnRK2 protein kinases, SRK2D/SnRK2.2, SRK2E/SnRK2.6/OST1 and SRK2I/SnRK2.3, involved in ABA signaling are essential for the control of seed development and dormancy.
    8. Results demonstrate that SnRK2.2 and SnRK2.3 are redundant but key protein kinases that mediate a major part of abscisic acid signaling in Arabidopsis.
      Title: Identification of two protein kinases required for abscisic acid regulation of seed germination, root growth, and gene expression in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001345807.1
    NM_126087.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within abscisic acid-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of abscisic acid-activated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of seed germination IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to abscisic acid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to gibberellin IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to osmotic stress IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to osmotic stress IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    sucrose nonfermenting 1(SNF1)-related protein kinase 2.3
    NP_001318893.1
    • sucrose nonfermenting 1(SNF1)-related protein kinase 2.3 (SNRK2.3); FUNCTIONS IN: protein kinase activity, kinase activity; INVOLVED IN: in 8 processes; LOCATED IN: cytosol, nucleus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636), Serine/threonine-protein kinase-like, plant (InterPro:IPR015740); BEST Arabidopsis thaliana protein match is: SNF1-related protein kinase 2.2 (TAIR:AT3G50500.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      26710302..26712971
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001345807.1 → NP_001318893.1  sucrose nonfermenting 1(SNF1)-related protein kinase 2.3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39193, Q8RWG9
      UniProtKB/TrEMBL
      A0A7G2FKI9

    2. NM_126087.5 → NP_201489.1  sucrose nonfermenting 1(SNF1)-related protein kinase 2.3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201489.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39193, Q8RWG9
      UniProtKB/TrEMBL
      A0A7G2FKI9
      Conserved Domains (2) summary
      smart00220
      Location:22 → 278
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14665
      Location:21 → 277
      STKc_SnRK2-3; Catalytic domain of the Serine/Threonine Kinases, Sucrose nonfermenting 1-related protein kinase subfamily 2, group 3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39193.1

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