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    Lad1 ladinin 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313325, updated on 27-Nov-2024

    Summary

    Official Symbol
    Lad1provided by RGD
    Official Full Name
    ladinin 1provided by RGD
    Primary source
    RGD:1310652
    See related
    EnsemblRapid:ENSRNOG00000009144 AllianceGenome:RGD:1310652
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable structural molecule activity. Predicted to be located in actin cytoskeleton. Orthologous to human LAD1 (ladinin 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 147.8), Lung (RPKM 32.8) and 4 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Lad1 in Genome Data Viewer
    Location:
    13q13
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (49801347..49815709)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (47249605..47263967)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (52645257..52659619)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481563 Neighboring gene troponin I1, slow skeletal type Neighboring gene troponin T2, cardiac type Neighboring gene plakophilin 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107942.2NP_001101412.2  ladinin-1

      See identical proteins and their annotated locations for NP_001101412.2

      Status: VALIDATED

      Source sequence(s)
      BC167044, BP504151, JAXUCZ010000013
      UniProtKB/TrEMBL
      A0A8I5ZPS3, A6ICG6, G3V779
      Related
      ENSRNOP00000091877.2, ENSRNOT00000100192.2
      Conserved Domains (1) summary
      pfam02029
      Location:367507
      Caldesmon; Caldesmon

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      49801347..49815709
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)