Dnm1l dynamin 1-like [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Dnm1lprovided by RGD
Official Full Name: dynamin 1-likeprovided by RGD
Primary source: RGD:620416
See related: EnsemblRapid:ENSRNOG00000001813 AllianceGenome:RGD:620416
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: DLP1; Drp1; Dnml1
Summary: Enables several functions, including BH2 domain binding activity; identical protein binding activity; and protein serine/threonine kinase binding activity. Involved in several processes, including positive regulation of cellular component organization; response to hypoxia; and synaptic vesicle recycling. Located in several cellular components, including Golgi membrane; clathrin-coated pit; and perinuclear region of cytoplasm. Is active in presynaptic endocytic zone membrane and synaptic vesicle membrane. Biomarker of chronic kidney disease; dental fluorosis; pulmonary fibrosis; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in encephalopathy due to defective mitochondrial and peroxisomal fission 1 and optic atrophy 5. Orthologous to human DNM1L (dynamin 1 like). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 422.0), Heart (RPKM 370.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 11q23

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	11	NC_086029.1 (98084049..98135663)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	11	NC_051346.1 (84581216..84632382)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	11	NC_005110.4 (88830968..88882271)

Chromosome 11 - NC_086029.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ERK1/2 Regulates Epileptic Seizures by Modulating the DRP1-Mediated Mitochondrial Dynamic.
Title: ERK1/2 Regulates Epileptic Seizures by Modulating the DRP1-Mediated Mitochondrial Dynamic.
AKAP1 alleviates VSMC phenotypic modulation and neointima formation by inhibiting Drp1-dependent mitochondrial fission.
Title: AKAP1 alleviates VSMC phenotypic modulation and neointima formation by inhibiting Drp1-dependent mitochondrial fission.
STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells.
Title: STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells.
A partial Drp1 knockout improves autophagy flux independent of mitochondrial function.
Title: A partial Drp1 knockout improves autophagy flux independent of mitochondrial function.
Hyperglycemia triggers RyR2-dependent alterations of mitochondrial calcium homeostasis in response to cardiac ischemia-reperfusion: Key role of DRP1 activation.
Title: Hyperglycemia triggers RyR2-dependent alterations of mitochondrial calcium homeostasis in response to cardiac ischemia-reperfusion: Key role of DRP1 activation.
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation.
Title: Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation.
Drp1/p53 interaction mediates p53 mitochondrial localization and dysfunction in septic cardiomyopathy.
Title: Drp1/p53 interaction mediates p53 mitochondrial localization and dysfunction in septic cardiomyopathy.
Role of KLF4/NDRG1/DRP1 axis in hypoxia-induced pulmonary hypertension.
Title: Role of KLF4/NDRG1/DRP1 axis in hypoxia-induced pulmonary hypertension.
PINK1 Phosphorylates Drp1(S616) to Improve Mitochondrial Fission and Inhibit the Progression of Hypertension-Induced HFpEF.
Title: PINK1 Phosphorylates Drp1(S616) to Improve Mitochondrial Fission and Inhibit the Progression of Hypertension-Induced HFpEF.
Swimming Exercise Alleviates Endothelial Mitochondrial Fragmentation via Inhibiting Dynamin-Related Protein-1 to Improve Vascular Function in Hypertension.
Title: Swimming Exercise Alleviates Endothelial Mitochondrial Fragmentation via Inhibiting Dynamin-Related Protein-1 to Improve Vascular Function in Hypertension.

Submit: New GeneRIF Correction See all GeneRIFs (91)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables BH2 domain binding	IPI Inferred from Physical Interaction more info	PubMed
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTP-dependent protein binding	ISO Inferred from Sequence Orthology more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables GTPase activity	ISO Inferred from Sequence Orthology more info
enables GTPase activity	ISS Inferred from Sequence or Structural Similarity more info
enables clathrin binding	IPI Inferred from Physical Interaction more info	PubMed
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables lipid binding	IEA Inferred from Electronic Annotation more info
enables membrane scission GTPase motor activity	IEA Inferred from Electronic Annotation more info
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info
enables protein homodimerization activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein serine/threonine kinase binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein-containing complex binding	IPI Inferred from Physical Interaction more info	PubMed
enables small GTPase binding	ISO Inferred from Sequence Orthology more info
enables ubiquitin protein ligase binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within calcium ion transport	ISO Inferred from Sequence Orthology more info
involved_in cellular response to hypoxia	IEP Inferred from Expression Pattern more info	PubMed
involved_in cellular response to lipid	IEP Inferred from Expression Pattern more info	PubMed
involved_in endocytosis	IBA Inferred from Biological aspect of Ancestor more info
NOT involved_in endoplasmic reticulum organization	ISO Inferred from Sequence Orthology more info
involved_in heart contraction	ISO Inferred from Sequence Orthology more info
involved_in intracellular distribution of mitochondria	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular distribution of mitochondria	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intracellular distribution of mitochondria	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial fission	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mitochondrial fission	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial fission	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial fission	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial fragmentation involved in apoptotic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial fragmentation involved in apoptotic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrial fragmentation involved in apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial membrane fission	ISO Inferred from Sequence Orthology more info
involved_in mitochondrion organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within mitochondrion organization	ISO Inferred from Sequence Orthology more info
involved_in mitochondrion organization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within mitocytosis	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of mitochondrial fusion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in peroxisome fission	IBA Inferred from Biological aspect of Ancestor more info
involved_in peroxisome fission	ISO Inferred from Sequence Orthology more info
involved_in peroxisome fission	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of dendritic spine morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of mitochondrial fission	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of mitochondrial fission	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of neutrophil chemotaxis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of protein secretion	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of synaptic vesicle endocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of synaptic vesicle exocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein complex oligomerization	ISO Inferred from Sequence Orthology more info
involved_in protein complex oligomerization	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within protein localization to mitochondrion	ISO Inferred from Sequence Orthology more info
involved_in protein localization to mitochondrion	ISO Inferred from Sequence Orthology more info
involved_in regulation of ATP metabolic process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of gene expression	ISO Inferred from Sequence Orthology more info
involved_in regulation of mitochondrion organization	ISO Inferred from Sequence Orthology more info
involved_in regulation of mitophagy	ISO Inferred from Sequence Orthology more info
involved_in regulation of peroxisome organization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of ubiquitin protein ligase activity	ISO Inferred from Sequence Orthology more info
involved_in response to endoplasmic reticulum stress	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to flavonoid	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to hypobaric hypoxia	IEP Inferred from Expression Pattern more info	PubMed
involved_in rhythmic process	IEA Inferred from Electronic Annotation more info
involved_in synaptic vesicle endocytosis	IDA Inferred from Direct Assay more info	PubMed
involved_in synaptic vesicle endocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in synaptic vesicle recycling via endosome	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
located_in Golgi membrane	IDA Inferred from Direct Assay more info	PubMed
located_in brush border	ISO Inferred from Sequence Orthology more info
NOT part_of clathrin coat of trans-Golgi network vesicle	IDA Inferred from Direct Assay more info	PubMed
located_in clathrin-coated pit	IDA Inferred from Direct Assay more info	PubMed
located_in clathrin-coated pit	IEA Inferred from Electronic Annotation more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info
located_in endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed
NOT located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule	ISO Inferred from Sequence Orthology more info
located_in mitochondrial membrane	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial outer membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrial outer membrane	ISS Inferred from Sequence or Structural Similarity more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion-derived vesicle	ISO Inferred from Sequence Orthology more info
located_in perinuclear region of cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in perinuclear region of cytoplasm	ISO Inferred from Sequence Orthology more info
located_in peroxisome	IDA Inferred from Direct Assay more info	PubMed
located_in peroxisome	IEA Inferred from Electronic Annotation more info
located_in peroxisome	ISO Inferred from Sequence Orthology more info
located_in peroxisome	ISS Inferred from Sequence or Structural Similarity more info
NOT located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
is_active_in presynaptic endocytic zone membrane	IDA Inferred from Direct Assay more info	PubMed
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info
located_in secretory vesicle	IDA Inferred from Direct Assay more info	PubMed
is_active_in synaptic vesicle membrane	IDA Inferred from Direct Assay more info	PubMed
located_in synaptic vesicle membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dynamin-1-like protein

Names: C-terminal region; N-terminal region; dynamin-like protein 1; dynamin-related protein 1

NP_446107.2

EC 3.6.5.5

XP_038943816.1

EC 3.6.5.5

XP_038943817.1

EC 3.6.5.5

XP_038943818.1

EC 3.6.5.5

XP_038943819.1

EC 3.6.5.5

XP_038943820.1

EC 3.6.5.5

XP_038943821.1

EC 3.6.5.5

XP_038943822.1

EC 3.6.5.5

XP_038943823.1

EC 3.6.5.5

XP_038943824.1

EC 3.6.5.5

XP_038943825.1

EC 3.6.5.5

XP_038943826.1

EC 3.6.5.5

XP_038943827.1

EC 3.6.5.5

XP_038943828.1

EC 3.6.5.5

XP_038943829.1

EC 3.6.5.5

XP_063126304.1

EC 3.6.5.5

XP_063126305.1

EC 3.6.5.5

XP_063126306.1

EC 3.6.5.5

XP_063126307.1

EC 3.6.5.5

XP_063126308.1

EC 3.6.5.5

XP_063126309.1

EC 3.6.5.5

XP_063126310.1

EC 3.6.5.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053655.3 → NP_446107.2 dynamin-1-like protein

See identical proteins and their annotated locations for NP_446107.2

Status: PROVISIONAL

Source sequence(s)

BC085843

UniProtKB/TrEMBL

A0A8I5ZNF9

Related

ENSRNOP00000078603.2, ENSRNOT00000101129.2

Conserved Domains (4) summary

cd08771
Location:23 → 302

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

COG0699
Location:88 → 709

CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]

pfam01031
Location:227 → 510

Dynamin_M; Dynamin central region

pfam02212
Location:622 → 710

GED; Dynamin GTPase effector domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086029.1 Reference GRCr8

Range

98084049..98135663

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039087888.2 → XP_038943816.1 dynamin-1-like protein isoform X1

UniProtKB/TrEMBL

A0A8I5ZNF9

Related

ENSRNOP00000002478.6, ENSRNOT00000002478.9

Conserved Domains (3) summary

cd08771
Location:23 → 321

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:245 → 529

Dynamin_M; Dynamin central region

pfam02212
Location:667 → 755

GED; Dynamin GTPase effector domain
XM_039087890.2 → XP_038943818.1 dynamin-1-like protein isoform X3

UniProtKB/TrEMBL

A0A8I5ZNF9

Conserved Domains (4) summary

cd08771
Location:23 → 321

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:245 → 529

Dynamin_M; Dynamin central region

pfam02212
Location:656 → 744

GED; Dynamin GTPase effector domain

NF033761
Location:540 → 652

gliding_GltJ; adventurous gliding motility protein GltJ
XM_039087894.2 → XP_038943822.1 dynamin-1-like protein isoform X8

UniProtKB/TrEMBL

A0A8I5ZNF9

Conserved Domains (3) summary

cd08771
Location:23 → 321

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:245 → 529

Dynamin_M; Dynamin central region

pfam02212
Location:641 → 729

GED; Dynamin GTPase effector domain
XM_039087897.2 → XP_038943825.1 dynamin-1-like protein isoform X11

UniProtKB/TrEMBL

A0A8I5ZNF9

Conserved Domains (3) summary

cd08771
Location:23 → 321

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:245 → 529

Dynamin_M; Dynamin central region

pfam02212
Location:630 → 718

GED; Dynamin GTPase effector domain
XM_039087891.2 → XP_038943819.1 dynamin-1-like protein isoform X4

UniProtKB/TrEMBL

A0A8I5ZNF9

Conserved Domains (3) summary

cd08771
Location:23 → 308

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:232 → 516

Dynamin_M; Dynamin central region

pfam02212
Location:654 → 742

GED; Dynamin GTPase effector domain
XM_063270234.1 → XP_063126304.1 dynamin-1-like protein isoform X7

UniProtKB/TrEMBL

A0A8I5ZNF9
XM_039087898.2 → XP_038943826.1 dynamin-1-like protein isoform X12

UniProtKB/TrEMBL

A0A8I5ZNF9

Conserved Domains (3) summary

cd08771
Location:23 → 308

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:232 → 516

Dynamin_M; Dynamin central region

pfam02212
Location:628 → 716

GED; Dynamin GTPase effector domain
XM_063270235.1 → XP_063126305.1 dynamin-1-like protein isoform X14

UniProtKB/TrEMBL

A0A8I5ZNF9
XM_039087889.2 → XP_038943817.1 dynamin-1-like protein isoform X2

UniProtKB/Swiss-Prot

O35303, O35318, O35319, O35320, O35321, O35322, O35323, Q5U2W1, Q792T7, Q9R234, Q9R277

UniProtKB/TrEMBL

A0A8I5ZNF9

Related

ENSRNOP00000079426.1, ENSRNOT00000097906.2

Conserved Domains (3) summary

cd08771
Location:23 → 315

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:239 → 523

Dynamin_M; Dynamin central region

pfam02212
Location:661 → 749

GED; Dynamin GTPase effector domain
XM_039087892.2 → XP_038943820.1 dynamin-1-like protein isoform X5

UniProtKB/TrEMBL

A0A8I5ZNF9

Related

ENSRNOP00000002482.7, ENSRNOT00000002482.9

Conserved Domains (4) summary

cd08771
Location:23 → 315

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:239 → 523

Dynamin_M; Dynamin central region

pfam02212
Location:650 → 738

GED; Dynamin GTPase effector domain

NF033761
Location:534 → 646

gliding_GltJ; adventurous gliding motility protein GltJ
XM_039087896.2 → XP_038943824.1 dynamin-1-like protein isoform X10

UniProtKB/TrEMBL

A0A8I5ZNF9

Conserved Domains (3) summary

cd08771
Location:23 → 315

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:239 → 523

Dynamin_M; Dynamin central region

pfam02212
Location:635 → 723

GED; Dynamin GTPase effector domain
XM_039087899.2 → XP_038943827.1 dynamin-1-like protein isoform X13

UniProtKB/TrEMBL

A0A8I5ZNF9

Conserved Domains (3) summary

cd08771
Location:23 → 315

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:239 → 523

Dynamin_M; Dynamin central region

pfam02212
Location:624 → 712

GED; Dynamin GTPase effector domain
XM_039087893.2 → XP_038943821.1 dynamin-1-like protein isoform X6

UniProtKB/TrEMBL

A0A8I5ZNF9

Related

ENSRNOP00000110808.1, ENSRNOT00000172935.1

Conserved Domains (3) summary

cd08771
Location:23 → 302

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:226 → 510

Dynamin_M; Dynamin central region

pfam02212
Location:648 → 736

GED; Dynamin GTPase effector domain
XM_039087895.2 → XP_038943823.1 dynamin-1-like protein isoform X9

UniProtKB/TrEMBL

A0A8I5ZNF9, A0A8L2Q0G8

Conserved Domains (4) summary

cd08771
Location:23 → 302

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:226 → 510

Dynamin_M; Dynamin central region

pfam02212
Location:637 → 725

GED; Dynamin GTPase effector domain

NF033761
Location:521 → 633

gliding_GltJ; adventurous gliding motility protein GltJ
XM_039087900.2 → XP_038943828.1 dynamin-1-like protein isoform X15

UniProtKB/TrEMBL

A0A8I5ZNF9

Related

ENSRNOP00000002477.7, ENSRNOT00000002477.10

Conserved Domains (3) summary

cd08771
Location:23 → 302

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:226 → 510

Dynamin_M; Dynamin central region

pfam02212
Location:611 → 699

GED; Dynamin GTPase effector domain
XM_063270236.1 → XP_063126306.1 dynamin-1-like protein isoform X16

UniProtKB/TrEMBL

A0A8I5ZNF9
XM_039087901.2 → XP_038943829.1 dynamin-1-like protein isoform X16

UniProtKB/TrEMBL

A0A8I5ZNF9

Conserved Domains (3) summary

cd08771
Location:1 → 153

DLP_1; Dynamin_like protein family includes dynamins and Mx proteins

pfam01031
Location:77 → 361

Dynamin_M; Dynamin central region

pfam02212
Location:499 → 587

GED; Dynamin GTPase effector domain
XM_063270237.1 → XP_063126307.1 dynamin-1-like protein isoform X17

UniProtKB/TrEMBL

A0A8I5ZNF9
XM_063270238.1 → XP_063126308.1 dynamin-1-like protein isoform X18
XM_063270240.1 → XP_063126310.1 dynamin-1-like protein isoform X19
XM_063270239.1 → XP_063126309.1 dynamin-1-like protein isoform X19