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    Pvf3 PDGF- and VEGF-related factor 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33995, updated on 17-Dec-2024

    Summary

    Official Symbol
    Pvf3provided by FlyBase
    Official Full Name
    PDGF- and VEGF-related factor 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0085407
    Locus tag
    Dmel_CG34378
    See related
    AllianceGenome:FB:FBgn0085407
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13781; CG13782; CG13783; CG31629; CG34378; CG4492; Dmel\CG34378; DmVEGF-3; Pvf; PVF; pvf3; PVF3; PVFs; VEGF; Vegf27Ca; VEGF27Ca
    Old locus tag
    CG13783; CG31629; Dmel_CG13783; Dmel_CG31629
    Summary
    Predicted to enable vascular endothelial growth factor receptor binding activity. Involved in several processes, including hemocyte migration; neurogenesis; and positive regulation of cell size. Acts upstream of with a positive effect on neuron remodeling. Located in extracellular space. Is expressed in several structures, including Malpighian tubule; Malpighian tubule primordium; anlage in statu nascendi; anterior-posterior subdivision of organism; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Pvf3 in Genome Data Viewer
    Location:
    27E1-27E3; 2-25 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7098188..7157695, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7098188..7157695, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44611 Neighboring gene PDGF- and VEGF-related factor 2 Neighboring gene long non-coding RNA:CR46196 Neighboring gene long non-coding RNA:CR44612 Neighboring gene long non-coding RNA:CR44610 Neighboring gene long non-coding RNA:CR46210

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in extracellular space PubMed 
    located_in membrane  

    General protein information

    Preferred Names
    PDGF- and VEGF-related factor 3
    Names
    CG34378-PA
    CG34378-PD
    CG34378-PE
    CG34378-PF
    Pvf3-PA
    Pvf3-PD
    Pvf3-PE
    Pvf3-PF

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7098188..7157695 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298777.1 → NP_001285706.1  PDGF- and VEGF-related factor 3, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285706.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q1WWB4, X2J909
      Conserved Domains (1) summary
      cd00135
      Location:451 → 534
      PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and ...
    2. NM_001103638.3 → NP_001097108.1  PDGF- and VEGF-related factor 3, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097108.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4M1, Q9VM42
      Conserved Domains (1) summary
      cd00135
      Location:295 → 378
      PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and ...
    3. NM_001103637.3 → NP_001097107.1  PDGF- and VEGF-related factor 3, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097107.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q1WWB4, Q9VM39
      Conserved Domains (1) summary
      cd00135
      Location:464 → 547
      PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and ...
    4. NM_001103639.4 → NP_001097109.2  PDGF- and VEGF-related factor 3, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097109.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4M1, Q9VM40
      Conserved Domains (1) summary
      cd00135
      Location:282 → 365
      PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and ...
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