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    CG8435 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36789, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8435provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034084
    Locus tag
    Dmel_CG8435
    See related
    AllianceGenome:FB:FBgn0034084
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8435
    Summary
    Predicted to be involved in RNA splicing. Predicted to be part of U2-type catalytic step 1 spliceosome. Is expressed in embryonic/larval salivary gland; embryonic/larval salivary gland body; and organism. Orthologous to human YJU2 (YJU2 splicing factor homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8435 in Genome Data Viewer
    Location:
    52F3-52F3; 2-78 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (16169600..16170861, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (12057105..12058366, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45994 Neighboring gene lambik Neighboring gene uncharacterized protein Neighboring gene Protein tyrosine phosphatase 52F Neighboring gene Lissencephaly-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Systematic identification of functional orthologs based on protein network comparison. Bandyopadhyay S, et al. Genome Res, 2006 Mar. PMID 16510899, Free PMC Article
    2. A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nybakken K, et al. Nat Genet, 2005 Dec. PMID 16311596, Free PMC Article
    3. Identification of genes associated with resilience/vulnerability to sleep deprivation and starvation in Drosophila. Thimgan MS, et al. Sleep, 2015 May 1. PMID 25409104, Free PMC Article
    4. Functional genomic analysis of the periodic transcriptome in the developing Drosophila wing. Liang L, et al. Dev Cell, 2014 Apr 14. PMID 24684830
    5. A genetic interaction map of cell cycle regulators. Billmann M, et al. Mol Biol Cell, 2016 Apr 15. PMID 26912791, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of U2-type catalytic step 1 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8435-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      16169600..16170861 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137248.4 → NP_611092.2  uncharacterized protein Dmel_CG8435 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611092.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JVH0
      Related
      FBpp0086387
      Conserved Domains (2) summary
      COG5134
      Location:7 → 170
      COG5134; Uncharacterized conserved protein [Function unknown]
      pfam04502
      Location:8 → 177
      DUF572; Family of unknown function (DUF572)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JVH0 Q7JVH0

    Gene LinkOut

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