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    Cpr65Au Cuticular protein 65Au [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 59158, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cpr65Auprovided by FlyBase
    Official Full Name
    Cuticular protein 65Auprovided by FlyBase
    Primary source
    FLYBASE:FBgn0042119
    Locus tag
    Dmel_CG18778
    See related
    AllianceGenome:FB:FBgn0042119
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH21145; CG18778; DmelCpr65Au; Dmel\CG18778
    Summary
    Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be active in chitin-based extracellular matrix. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cpr65Au in Genome Data Viewer
    Location:
    65A6-65A6; 3-16 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6131242..6132109, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6124342..6125209, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene lethal (3) malignant blood neoplasm Neighboring gene antisense RNA:CR46005 Neighboring gene Larval cuticle protein Neighboring gene Lcp65Ag2 Neighboring gene Lcp65Ag1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Population Genomics of sub-saharan Drosophila melanogaster: African diversity and non-African admixture. Pool JE, et al. PLoS Genet, 2012. PMID 23284287, Free PMC Article
    2. Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity. Ghosh AC, et al. Elife, 2020 Oct 27. PMID 33107824, Free PMC Article
    3. Elucidating the "Gravome": Quantitative Proteomic Profiling of the Response to Chronic Hypergravity in Drosophila. Hosamani R, et al. J Proteome Res, 2016 Dec 2. PMID 27648494
    4. The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Bellen HJ, et al. Genetics, 2004 Jun. PMID 15238527, Free PMC Article
    5. Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1. Zhang T, et al. J Cell Sci, 2015 Aug 1. PMID 26092939, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based larval cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of chitin-based larval cuticle ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chitin-based extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chitin-based extracellular matrix ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cuticular protein 65Au
    Names
    CG18778-PA
    CG18778-PB
    Cpr65Au-PA
    Cpr65Au-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6131242..6132109 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300024.1 → NP_001286953.1  cuticular protein 65Au, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286953.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9I7Q5
      Conserved Domains (1) summary
      pfam00379
      Location:42 → 98
      Chitin_bind_4; Insect cuticle protein

    2. NM_144404.2 → NP_652661.1  cuticular protein 65Au, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652661.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9I7Q5
      Related
      FBpp0076768
      Conserved Domains (1) summary
      pfam00379
      Location:42 → 98
      Chitin_bind_4; Insect cuticle protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9I7Q5 Q9I7Q5

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