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    CG2528 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35435, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2528provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032969
    Locus tag
    Dmel_CG2528
    See related
    AllianceGenome:FB:FBgn0032969
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG2528; lincRNA.224
    Summary
    Enables serine hydrolase activity. Predicted to be involved in proteolysis. Predicted to be active in cytosol. Orthologous to human PREP (prolyl endopeptidase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2528 in Genome Data Viewer
    Location:
    40D1-40D2; 2-54 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (21974749..21992933, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (21981480..21992933, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44803 Neighboring gene long non-coding RNA:CR44804 Neighboring gene long non-coding RNA:CR44916 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic analysis of dPsa, the Drosophila orthologue of puromycin-sensitive aminopeptidase, suggests redundancy of aminopeptidases. Schulz C, et al. Dev Genes Evol, 2001 Dec. PMID 11819115
    2. Hidden genetic variation shapes the structure of functional elements in Drosophila. Chakraborty M, et al. Nat Genet, 2018 Jan. PMID 29255259, Free PMC Article
    3. Comparative genomics reveals a constant rate of origination and convergent acquisition of functional retrogenes in Drosophila. Bai Y, et al. Genome Biol, 2007. PMID 17233920, Free PMC Article
    4. Parent genes of retrotransposition-generated gene duplicates in Drosophila melanogaster have distinct expression profiles. Langille MG, et al. Genomics, 2007 Sep. PMID 17628393
    5. Genome-wide view of cell fate specification: ladybird acts at multiple levels during diversification of muscle and heart precursors. Junion G, et al. Genes Dev, 2007 Dec 1. PMID 18056427, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    mobile_element

    • Loc: c21990843-21981738 mobile_element_type = transposon:roo{}CG2528[iso-1]

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables oligopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine hydrolase activity HDA PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2528-PE
    CG2528-PG
    NP_001303334.1
    NP_610129.3
    • unusual splice

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      21974749..21992933 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001316405.1 → NP_001303334.1  uncharacterized protein Dmel_CG2528, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0T7B3Z6, D5SHQ2
      Conserved Domains (2) summary
      pfam00326
      Location:516 → 670
      Peptidase_S9; Prolyl oligopeptidase family
      pfam02897
      Location:28 → 442
      Peptidase_S9_N; Prolyl oligopeptidase, N-terminal beta-propeller domain

    2. NM_136285.3 → NP_610129.3  uncharacterized protein Dmel_CG2528, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610129.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      D5SHQ2, Q9V9P5
      Conserved Domains (2) summary
      pfam00326
      Location:516 → 727
      Peptidase_S9; Prolyl oligopeptidase family
      pfam02897
      Location:28 → 442
      Peptidase_S9_N; Prolyl oligopeptidase, N-terminal beta-propeller domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0T7B3Z6 A0A0T7B3Z6
    Q9V9P5 Q9V9P5

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