Taf13 TBP-associated factor 13 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Taf13provided by FlyBase
Official Full Name: TBP-associated factor 13provided by FlyBase
Primary source: FLYBASE:FBgn0032847
Locus tag: Dmel_CG10756
See related: AllianceGenome:FB:FBgn0032847
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 38B.15; CG10756; Dmel\CG10756; dTAF[[II]]18; TAF; taf13; TAF13; Taf18; TAF18; TAF[[II]]; TAF[[II]]18; TFIID
Summary: Predicted to enable protein heterodimerization activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be part of transcription factor TFIID complex. Is expressed in several structures, including antennal anlage; antennal primordium; anterior endoderm; head epidermis primordium; and mesoderm. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 60. Orthologous to human TAF13 (TATA-box binding protein associated factor 13). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (20093088..20093849, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (20093088..20093849, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to RNA polymerase II general transcription initiation factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in transcription initiation at RNA polymerase II promoter	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
part_of transcription factor TFIID complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription factor TFIID complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Names: CG10756-PA; TBP-associated factor; TBP-associated factor 18kD; Taf13-PA

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The following sections contain reference sequences that belong to a specific genome build. Explain