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    HDG3 homeodomain GLABROUS 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817798, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HDG3
    Official Full Name
    homeodomain GLABROUS 3
    Primary source
    TAIR:AT2G32370
    Locus tag
    AT2G32370
    See related
    Araport:AT2G32370
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    homeodomain GLABROUS 3; T32F6.11; T32F6_11
    Summary
    Encodes a homeobox-leucine zipper family protein belonging to the HD-ZIP IV family. Together with ATML1 and PDF2, it is involved in cotyledon development.
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    Genomic context

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    See HDG3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (13740878..13746286)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Ubiquitin-like superfamily protein Neighboring gene Ubiquitin-like superfamily protein Neighboring gene Transmembrane protein 97, Putative Neighboring gene glutamate receptor 3.5 Neighboring gene glutamate receptor 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the class IV homeodomain-Leucine Zipper gene family in Arabidopsis. Nakamura M, et al. Plant Physiol, 2006 Aug. PMID 16778018, Free PMC Article
    2. AIL and HDG proteins act antagonistically to control cell proliferation. Horstman A, et al. Development, 2015 Feb 1. PMID 25564655
    3. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_128796.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_positive_effect cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cotyledon development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    homeodomain GLABROUS 3
    NP_180796.2
    • homeodomain GLABROUS 3 (HDG3); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent, cotyledon development; LOCATED IN: nucleus; EXPRESSED IN: fruit; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Homeobox, conserved site (InterPro:IPR017970), Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), Lipid-binding START (InterPro:IPR002913), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: homeodomain GLABROUS 2 (TAIR:AT1G05230.3); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13740878..13746286
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128796.3 → NP_180796.2  homeodomain GLABROUS 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180796.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A7LBA8, Q9ZV65
      UniProtKB/TrEMBL
      A0A5S9X3B8, A0A654EY49
      Conserved Domains (2) summary
      cd08875
      Location:247 → 471
      START_ArGLABRA2_like; C-terminal lipid-binding START domain of the Arabidopsis homeobox protein GLABRA 2 and related proteins
      pfam00046
      Location:71 → 125
      Homeobox; Homeobox domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZV65.2

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