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    CSP3 cold shock domain protein 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816297, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CSP3
    Official Full Name
    cold shock domain protein 3
    Primary source
    TAIR:AT2G17870
    Locus tag
    AT2G17870
    See related
    Araport:AT2G17870
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS COLD SHOCK DOMAIN PROTEIN 3; ATCSP3; cold shock domain protein 3; T13L16.11; T13L16_11
    Summary
    Encodes COLD SHOCK DOMAIN PROTEIN 3 (CSP3), involved in the acquisition of freezing tolerance.
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    Genomic context

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    See CSP3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (7763528..7765276, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Rhodanese/Cell cycle control phosphatase superfamily protein Neighboring gene Pathogenesis-related thaumatin superfamily protein Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene calcium-dependent protein kinase 16

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cold shock domain protein 3 regulates freezing tolerance in Arabidopsis thaliana. Kim MH, et al. J Biol Chem, 2009 Aug 28. PMID 19556243, Free PMC Article
    2. A Cold-Inducible DEAD-Box RNA Helicase from Arabidopsis thaliana Regulates Plant Growth and Development under Low Temperature. Liu Y, et al. PLoS One, 2016. PMID 27116354, Free PMC Article
    3. Effects of mutations in the Arabidopsis Cold Shock Domain Protein 3 (AtCSP3) gene on leaf cell expansion. Yang Y, et al. J Exp Bot, 2012 Aug. PMID 22888122, Free PMC Article
    4. Conservation of the cold shock domain protein family in plants. Karlson D, et al. Plant Physiol, 2003 Jan. PMID 12529510, Free PMC Article
    5. Interactome analysis reveals versatile functions of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 in RNA processing within the nucleus and cytoplasm. Kim MH, et al. Cell Stress Chaperones, 2013 Jul. PMID 23334891, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This study identified one of the Arabidopsis thaliana DEAD-box RNA helicases, AtRH7, as an interactor of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 (AtCSP3), which is an RNA chaperone involved in cold adaptation. [AtCSP3]
      Title: A Cold-Inducible DEAD-Box RNA Helicase from Arabidopsis thaliana Regulates Plant Growth and Development under Low Temperature.
    2. AtCSP3 is functionally linked to the regulation of leaf length by affecting LNG1 transcript accumulation during leaf development.
      Title: Effects of mutations in the Arabidopsis Cold Shock Domain Protein 3 (AtCSP3) gene on leaf cell expansion.
    3. AtCSP3 interacts with CONSTANS-LIKE protein 15 and nuclear poly(A)-binding proteins in nuclear speckles.
      Title: Interactome analysis reveals versatile functions of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 in RNA processing within the nucleus and cytoplasm.
    4. CSP3 knock-out mutant was sensitive to freezing compared with wild-type plants.
      Title: Cold shock domain protein 3 regulates freezing tolerance in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_127341.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA duplex unwinding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in cold acclimation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cold shock domain protein 3
    NP_565427.1
    • cold shock domain protein 3 (CSP3); FUNCTIONS IN: DNA binding, zinc ion binding, nucleic acid binding; INVOLVED IN: response to cold, DNA duplex unwinding; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), Cold-shock conserved site (InterPro:IPR019844), Zinc finger, CCHC retroviral-type (InterPro:IPR013084), Cold shock protein (InterPro:IPR011129), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Zinc finger, CCHC-type (InterPro:IPR001878), Cold-shock protein, DNA-binding (InterPro:IPR002059); BEST Arabidopsis thaliana protein match is: cold shock domain protein 1 (TAIR:AT4G36020.1); Has 72472 Blast hits to 41123 proteins in 2889 species: Archae - 51; Bacteria - 27281; Metazoa - 11105; Fungi - 2852; Plants - 6181; Viruses - 14957; Other Eukaryotes - 10045 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      7763528..7765276 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127341.4 → NP_565427.1  cold shock domain protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565427.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94C69
      Conserved Domains (2) summary
      PTZ00368
      Location:132 → 299
      PTZ00368; universal minicircle sequence binding protein (UMSBP); Provisional
      pfam00313
      Location:13 → 77
      CSD; 'Cold-shock' DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94C69.1

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