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    RA-5 RAS 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837023, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RA-5
    Official Full Name
    RAS 5
    Primary source
    TAIR:AT1G02130
    Locus tag
    AT1G02130
    See related
    Araport:AT1G02130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARA-5; ARA5; ARABIDOPSIS RAS 5; ARABIDOPSIS THALIANA RAB D2A; ARABIDOPSIS THALIANA RESPONSIVE TO ABSCISIC ACID 1B; ATRAB1B; ATRABD2A; RAB D2A; RABD2A; RAS 5; T7I23.6; T7I23_6
    Summary
    Belongs to the Rab1 GTPase subfamily. This small GTP-binding protein is required in ER to Golgi transportation.
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    Genomic context

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    See RA-5 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (399983..401919, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Leucine carboxyl methyltransferase Neighboring gene bZIP domain class transcription factor (DUF630 and DUF632) Neighboring gene GRAM domain family protein Neighboring gene ncRNA Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A rab1 GTPase is required for transport between the endoplasmic reticulum and golgi apparatus and for normal golgi movement in plants. Batoko H, et al. Plant Cell, 2000 Nov. PMID 11090219, Free PMC Article
    2. Genetic evidence that the higher plant Rab-D1 and Rab-D2 GTPases exhibit distinct but overlapping interactions in the early secretory pathway. Pinheiro H, et al. J Cell Sci, 2009 Oct 15. PMID 19789181, Free PMC Article
    3. Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2004 Jul. PMID 15060130
    4. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article
    5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Rab-D1 and Rab-D2 subclasses have overlapping functions in the early secretory pathway. [Rab-D2a]
      Title: Genetic evidence that the higher plant Rab-D1 and Rab-D2 GTPases exhibit distinct but overlapping interactions in the early secretory pathway.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_100093.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in trans-Golgi network membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RAS 5
    NP_171715.1
    • RAS 5 (RA-5); FUNCTIONS IN: GTP binding; INVOLVED IN: response to cadmium ion, ER to Golgi vesicle-mediated transport; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog 1A (TAIR:AT5G47200.1); Has 30420 Blast hits to 30350 proteins in 816 species: Archae - 27; Bacteria - 199; Metazoa - 15882; Fungi - 4318; Plants - 3658; Viruses - 20; Other Eukaryotes - 6316 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      399983..401919 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100093.4 → NP_171715.1  RAS 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171715.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P28188, Q940Z7
      UniProtKB/TrEMBL
      A0A178WIV4, A0A5S9S533
      Conserved Domains (1) summary
      cd01869
      Location:7 → 172
      Rab1_Ypt1; Rab GTPase family 1 includes the yeast homolog Ypt1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P28188.3

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