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    PAP12 purple acid phosphatase 12 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817261, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAP12
    Official Full Name
    purple acid phosphatase 12
    Primary source
    TAIR:AT2G27190
    Locus tag
    AT2G27190
    See related
    Araport:AT2G27190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA PURPLE ACID PHOSPHATASE 1; ATPAP1; ATPAP12; PAP1; PURPLE ACID PHOSPHATASE 1; purple acid phosphatase 12; PURPLE ACID PHOSPHATASE 12; SECRETED PURPLE ACID PHOSPHATASE PRECURSOR; T22O13.4; T22O13_4
    Summary
    Encodes a root-secreted purple acid phosphatase involved in extracellular phosphate-scavenging.
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    Genomic context

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    See PAP12 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (11621222..11623618, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Structural maintenance of chromosomes (SMC) family protein Neighboring gene uncharacterized protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene BRI1 suppressor 1 (BSU1)-like 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The secreted purple acid phosphatase isozymes AtPAP12 and AtPAP26 play a pivotal role in extracellular phosphate-scavenging by Arabidopsis thaliana. Robinson WD, et al. J Exp Bot, 2012 Nov. PMID 23125358, Free PMC Article
    2. Biochemical and molecular characterization of AtPAP12 and AtPAP26: the predominant purple acid phosphatase isozymes secreted by phosphate-starved Arabidopsis thaliana. Tran HT, et al. Plant Cell Environ, 2010 Nov. PMID 20545876
    3. A chloroplast phosphate transporter, PHT2;1, influences allocation of phosphate within the plant and phosphate-starvation responses. Versaw WK, et al. Plant Cell, 2002 Aug. PMID 12172020, Free PMC Article
    4. Comparative genetic analysis of Arabidopsis purple acid phosphatases AtPAP10, AtPAP12, and AtPAP26 provides new insights into their roles in plant adaptation to phosphate deprivation. Wang L, et al. J Integr Plant Biol, 2014 Mar. PMID 24528675
    5. Purple acid phosphatases of Arabidopsis thaliana. Comparative analysis and differential regulation by phosphate deprivation. Li D, et al. J Biol Chem, 2002 Aug 2. PMID 12021284

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtPAP12 and AtPAP26 are two major intracellular and secreted acid phosphatases (APases) in Arabidopsis while AtPAP10 is mainly a secreted APase.
      Title: Comparative genetic analysis of Arabidopsis purple acid phosphatases AtPAP10, AtPAP12, and AtPAP26 provides new insights into their roles in plant adaptation to phosphate deprivation.
    2. An Arabidopsis thaliana purple acid phosphatase atpap26/atpap12 T-DNA double insertion mutant impaired growth and produced >60 and >30% decreases in root secretory APase activity and rosette total inorganic phosphorus concentration, respectively.
      Title: The secreted purple acid phosphatase isozymes AtPAP12 and AtPAP26 play a pivotal role in extracellular phosphate-scavenging by Arabidopsis thaliana.
    3. AtPAP12 and AtPAP26 facilitate Pi scavenging from soil-localized organophosphates during nutritional Pi deprivation.
      Title: Biochemical and molecular characterization of AtPAP12 and AtPAP26: the predominant purple acid phosphatase isozymes secreted by phosphate-starved Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    General gene information

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    NM_128277.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables acid phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables acid phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to phosphate starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    purple acid phosphatase 12
    NP_180287.2
    • purple acid phosphatase 12 (PAP12); FUNCTIONS IN: protein serine/threonine phosphatase activity, acid phosphatase activity; INVOLVED IN: cellular response to phosphate starvation; LOCATED IN: plant-type cell wall; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Purple acid phosphatase, N-terminal (InterPro:IPR015914), Metallophosphoesterase (InterPro:IPR004843), Purple acid phosphatase-like, N-terminal (InterPro:IPR008963); BEST Arabidopsis thaliana protein match is: purple acid phosphatase 10 (TAIR:AT2G16430.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      11621222..11623618 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128277.5 → NP_180287.2  purple acid phosphatase 12 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180287.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q38924, Q42349, Q540Q7, Q8VZC6, Q9SHS9
      UniProtKB/TrEMBL
      A0A654EWP1
      Conserved Domains (3) summary
      cd00839
      Location:157 → 455
      MPP_PAPs; purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain
      pfam00149
      Location:161 → 360
      Metallophos; Calcineurin-like phosphoesterase
      pfam16656
      Location:60 → 149
      Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q38924.3

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