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    CCR2 cinnamoyl coa reductase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844421, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CCR2
    Official Full Name
    cinnamoyl coa reductase
    Primary source
    TAIR:AT1G80820
    Locus tag
    AT1G80820
    See related
    Araport:AT1G80820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCCR2; cinnamoyl coa reductase; F23A5.17; F23A5_17
    Summary
    Encodes an cinnamoyl CoA reductase isoform. Involved in lignin biosynthesis.
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    Genomic context

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    See CCR2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (30370474..30372799)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene Tudor/PWWP/MBT superfamily protein Neighboring gene natural resistance-associated macrophage protein 1 Neighboring gene WRKY DNA-binding protein 40 Neighboring gene DNA glycosylase superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two cinnamoyl-CoA reductase (CCR) genes from Arabidopsis thaliana are differentially expressed during development and in response to infection with pathogenic bacteria. Lauvergeat V, et al. Phytochemistry, 2001 Aug. PMID 11430991
    2. AtGRP7, a nuclear RNA-binding protein as a component of a circadian-regulated negative feedback loop in Arabidopsis thaliana. Heintzen C, et al. Proc Natl Acad Sci U S A, 1997 Aug 5. PMID 9238008, Free PMC Article
    3. Genes encoding glycine-rich Arabidopsis thaliana proteins with RNA-binding motifs are influenced by cold treatment and an endogenous circadian rhythm. Carpenter CD, et al. Plant Physiol, 1994 Mar. PMID 7513083, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_106730.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cinnamoyl-CoA reductase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in circadian rhythm IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within lignin biosynthetic process NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in negative regulation of circadian rhythm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phenylpropanoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    cinnamoyl coa reductase
    NP_178197.1
    • cinnamoyl coa reductase (CCR2); CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: cinnamoyl coa reductase 1 (TAIR:AT1G15950.1); Has 10779 Blast hits to 10766 proteins in 1817 species: Archae - 140; Bacteria - 4512; Metazoa - 410; Fungi - 946; Plants - 2512; Viruses - 14; Other Eukaryotes - 2245 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      30370474..30372799
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001335015.1 → NP_001323345.1  cinnamoyl coa reductase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WG92, A0A1P8AWR1, A0A5S9WW63

    2. NM_106730.4 → NP_178197.1  cinnamoyl coa reductase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178197.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LBL0, Q9C5Y1, Q9SAH9
      UniProtKB/TrEMBL
      A0A178WG92, A0A5S9WW63
      Conserved Domains (1) summary
      cl21454
      Location:5 → 332
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SAH9.1

    Gene LinkOut

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