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    ABCC6 multidrug resistance-associated protein 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820497, updated on 18-Sep-2024

    Summary

    Official Symbol
    ABCC6
    Official Full Name
    multidrug resistance-associated protein 8
    Primary source
    TAIR:AT3G13090
    Locus tag
    AT3G13090
    See related
    Araport:AT3G13090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATABCC6; ATMRP8; ATP-binding cassette C6; MRP8; multidrug resistance-associated protein 8
    Summary
    member of MRP subfamily
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    Genomic context

    See ABCC6 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (4202811..4208261, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene CBS domain-containing protein / transporter associated domain-containing protein Neighboring gene uncharacterized protein Neighboring gene multidrug resistance-associated protein 3 Neighboring gene miscRNA Neighboring gene multidrug resistance-associated protein 7 Neighboring gene serine acetyltransferase 2;2

    Bibliography

    Related articles in PubMed

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_112148.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type xenobiotic transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    multidrug resistance-associated protein 8
    NP_187916.3
    • multidrug resistance-associated protein 8 (MRP8); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, transmembrane transport; LOCATED IN: plasma membrane; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 7 (TAIR:AT3G13100.1); Has 618731 Blast hits to 341231 proteins in 4024 species: Archae - 11229; Bacteria - 503340; Metazoa - 11410; Fungi - 6818; Plants - 5765; Viruses - 13; Other Eukaryotes - 80156 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4202811..4208261 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112148.4NP_187916.3  multidrug resistance-associated protein 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187916.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VZZ4, Q9LK63
      UniProtKB/TrEMBL
      A0A5S9XBV2, A0A654F6L0
      Conserved Domains (4) summary
      cd03244
      Location:12171437
      ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
      cd03250
      Location:601801
      ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
      PLN03232
      Location:671452
      PLN03232; ABC transporter C family member; Provisional
      cl00549
      Location:9021173
      ABC_membrane; ABC transporter transmembrane region