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    CAP1 cyclase associated protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829600, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CAP1
    Official Full Name
    cyclase associated protein 1
    Primary source
    TAIR:AT4G34490
    Locus tag
    AT4G34490
    See related
    Araport:AT4G34490
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCAP1; CAP 1; cyclase associated protein 1; T4L20.70; T4L20_70
    Summary
    CYCLASE ASSOCIATED PROTEIN
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    Genomic context

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    See CAP1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Sequence:
    Chromosome: 4; NC_003075.7 (16484470..16487574, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene O-Glycosyl hydrolases family 17 protein Neighboring gene SKP1-like 12 Neighboring gene Protein kinase superfamily protein Neighboring gene 3-ketoacyl-CoA synthase 17

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Knockout of cyclase-associated protein CAP1 confers tolerance towards salt and osmotic stress in Arabidopsis. Zhang Q, et al. J Plant Physiol, 2023 Jun. PMID 37087999
    2. Arabidopsis CAP1 - a key regulator of actin organisation and development. Deeks MJ, et al. J Cell Sci, 2007 Aug 1. PMID 17635992
    3. Identification of Arabidopsis cyclase-associated protein 1 as the first nucleotide exchange factor for plant actin. Chaudhry F, et al. Mol Biol Cell, 2007 Aug. PMID 17538023, Free PMC Article
    4. Arabidopsis CAP regulates the actin cytoskeleton necessary for plant cell elongation and division. Barrero RA, et al. Plant Cell, 2002 Jan. PMID 11826305, Free PMC Article
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Knockout of cyclase-associated protein CAP1 confers tolerance towards salt and osmotic stress in Arabidopsis.
      Title: Knockout of cyclase-associated protein CAP1 confers tolerance towards salt and osmotic stress in Arabidopsis.
    2. findings show that mutants in CAP1 display a phenotype that establishes CAP1 as a fundamental facilitator of actin dynamics over a wide range of plant tissues
      Title: Arabidopsis CAP1 - a key regulator of actin organisation and development.
    3. These results and the understanding of other actin-binding proteins implicate CAP1 as a central player in regulating the pool of unpolymerized ATP-actin.
      Title: Identification of Arabidopsis cyclase-associated protein 1 as the first nucleotide exchange factor for plant actin.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_001342287.1
    NM_119614.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables actin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin cytoskeleton organization TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cyclase associated protein 1
    NP_195175.1
    • cyclase associated protein 1 (CAP1); CONTAINS InterPro DOMAIN/s: Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal (InterPro:IPR016098), CAP, conserved site (InterPro:IPR018106), Adenylate cyclase-associated CAP (InterPro:IPR001837), CARP motif (InterPro:IPR006599), Adenylate cyclase-associated CAP, N-terminal (InterPro:IPR013992), C-CAP/cofactor C-like domain (InterPro:IPR017901), Adenylate cyclase-associated CAP, C-terminal (InterPro:IPR013912); Has 618 Blast hits to 612 proteins in 211 species: Archae - 0; Bacteria - 2; Metazoa - 296; Fungi - 160; Plants - 51; Viruses - 0; Other Eukaryotes - 109 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      16484470..16487574 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119614.6 → NP_195175.1  cyclase associated protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195175.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65902
      UniProtKB/TrEMBL
      A0A178UWX1, A0A5S9XYZ5, A0A654FVT5
      Conserved Domains (2) summary
      pfam01213
      Location:3 → 68
      CAP_N; Adenylate cyclase associated (CAP) N terminal
      pfam08603
      Location:316 → 473
      CAP_C; Adenylate cyclase associated (CAP) C terminal

    2. NM_001342287.1 → NP_001329504.1  cyclase associated protein 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B7W9, A0A654FVT5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O65902.1

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