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    PLDALPHA3 phospholipase D alpha 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832609, updated on 18-Sep-2024

    Summary

    Official Symbol
    PLDALPHA3
    Official Full Name
    phospholipase D alpha 3
    Primary source
    TAIR:AT5G25370
    Locus tag
    AT5G25370
    See related
    Araport:AT5G25370
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F18G18.110; F18G18_110; phospholipase D alpha 3
    Summary
    member of C2-PLD subfamily. Analyses on the gene structures/sequences, overall amino acid sequences, and domain structures indicate that PLDalpha3 is most closely related to other two PLDalphas than to other PLDs. Phylogenetic analysis has not identified a true ortholog for PLDalpha3. Involved in hyperosmotic response.
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    Genomic context

    See PLDALPHA3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (8803829..8807783, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene EIN3-binding F box protein 2 Neighboring gene uncharacterized protein Neighboring gene cyclin a2;1 Neighboring gene Integrase-type DNA-binding superfamily protein

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables N-acylphosphatidylethanolamine-specific phospholipase D activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phospholipase D activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables phospholipase D activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phospholipase D activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    phospholipase D alpha 3
    NP_001318645.1
    • phospholipase D alpha 3 (PLDALPHA3); FUNCTIONS IN: phospholipase D activity; INVOLVED IN: response to water deprivation, response to salt stress, response to abscisic acid stimulus, membrane lipid catabolic process; LOCATED IN: membrane; EXPRESSED IN: leaf apex, root, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Phospholipase D (InterPro:IPR015679), Phospholipase D, plant (InterPro:IPR011402), Phospholipase D/Transphosphatidylase (InterPro:IPR001736), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: phospholipase D alpha 1 (TAIR:AT3G15730.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      8803829..8807783 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343921.1NP_001331647.1  phospholipase D alpha 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P58766
      UniProtKB/TrEMBL
      A0A654G4K6
    2. NM_122446.2NP_197919.1  phospholipase D alpha 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197919.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P58766
      UniProtKB/TrEMBL
      A0A654G4K6
      Conserved Domains (4) summary
      PLN02270
      Location:3820
      PLN02270; phospholipase D alpha
      cd04015
      Location:5156
      C2_plant_PLD; C2 domain present in plant phospholipase D (PLD)
      pfam12357
      Location:739810
      PLD_C; Phospholipase D C terminal
      cl15239
      Location:500708
      PLDc_SF; Catalytic domain of phospholipase D superfamily proteins
    3. NM_001343922.1NP_001331648.1  phospholipase D alpha 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BEI1, A0A654G4K6
    4. NM_001343920.1NP_001318645.1  phospholipase D alpha 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P58766
      UniProtKB/TrEMBL
      A0A654G4K6