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    BCCP2 biotin carboxyl carrier protein 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831406, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BCCP2
    Official Full Name
    biotin carboxyl carrier protein 2
    Primary source
    TAIR:AT5G15530
    Locus tag
    AT5G15530
    See related
    Araport:AT5G15530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    biotin carboxyl carrier protein 2; BIOTIN CARBOXYL-CARRIER PROTEIN; CAC1-B; T20K14.140; T20K14_140
    Summary
    biotin carboxyl carrier protein isoform 2 (BCCP2) mRNA
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    Genomic context

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    See BCCP2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (5038563..5040840)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Ankyrin repeat family protein Neighboring gene TPX2 (targeting protein for Xklp2) protein family Neighboring gene Ribosomal protein S19e family protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reverse-genetic analysis of the two biotin-containing subunit genes of the heteromeric acetyl-coenzyme A carboxylase in Arabidopsis indicates a unidirectional functional redundancy. Li X, et al. Plant Physiol, 2011 Jan. PMID 21030508, Free PMC Article
    2. Design of a Seed-Specific Chimeric Promoter with a Modified Expression Profile to Improve Seed Oil Content. Aoyagi T, et al. Int J Mol Sci, 2018 Jun 5. PMID 29874815, Free PMC Article
    3. Brassicaceae express multiple isoforms of biotin carboxyl carrier protein in a tissue-specific manner. Thelen JJ, et al. Plant Physiol, 2001 Apr. PMID 11299381, Free PMC Article
    4. Chloroplast acetyl-CoA carboxylase activity is 2-oxoglutarate-regulated by interaction of PII with the biotin carboxyl carrier subunit. Feria Bourrellier AB, et al. Proc Natl Acad Sci U S A, 2010 Jan 5. PMID 20018655, Free PMC Article
    5. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. We constructed a chimeric promoter that starts to express in the early stage of seed development, and high-level expression is retained until the later stage by connecting the promoters of the biotin carboxyl carrier protein 2 (BCCP2) gene encoding the BCCP2 subunit of acetyl-CoA carboxylase and the fatty acid elongase 1 (FAE1) gene from Arabidopsis
      Title: Design of a Seed-Specific Chimeric Promoter with a Modified Expression Profile to Improve Seed Oil Content.
    2. BCCP1 protein can compensate for the lack of BCCP2, the absence of BCCP1 cannot be tolerated as BCCP2 levels are not sufficient to support heteromeric acetyl-coenzyme A carboxylase activity at a level that is required for normal growth and development.
      Title: Reverse-genetic analysis of the two biotin-containing subunit genes of the heteromeric acetyl-coenzyme A carboxylase in Arabidopsis indicates a unidirectional functional redundancy.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_121557.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables acetyl-CoA carboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables biotin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of acetyl-CoA carboxylase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 

    General protein information

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    Preferred Names
    biotin carboxyl carrier protein 2
    NP_568316.1
    • biotin carboxyl carrier protein 2 (BCCP2); FUNCTIONS IN: biotin binding; INVOLVED IN: fatty acid biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Biotin-binding site (InterPro:IPR001882), Single hybrid motif (InterPro:IPR011053), Acetyl-CoA biotin carboxyl carrier (InterPro:IPR001249), Biotin/lipoyl attachment (InterPro:IPR000089); BEST Arabidopsis thaliana protein match is: chloroplastic acetylcoenzyme A carboxylase 1 (TAIR:AT5G16390.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5038563..5040840
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121557.4 → NP_568316.1  biotin carboxyl carrier protein 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568316.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LF29, Q9LLC1
      UniProtKB/TrEMBL
      A0A178U9S1, A0A5S9Y4N9, A0A7G2F8L8
      Conserved Domains (1) summary
      PLN02983
      Location:1 → 255
      PLN02983; biotin carboxyl carrier protein of acetyl-CoA carboxylase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LLC1.1

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