VhaAC39-1 Vacuolar H[+] ATPase AC39 subunit 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: VhaAC39-1provided by FlyBase
Official Full Name: Vacuolar H[+] ATPase AC39 subunit 1provided by FlyBase
Primary source: FLYBASE:FBgn0285910
Locus tag: Dmel_CG2934
See related: AllianceGenome:FB:FBgn0285910
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-EST:GressD5; ATP6V0D1; CG2934; cho; Dmel\CG2934; V0d; vhaAC39; Vhaac39; VhaAC39; vhaAC39-1
Summary: Predicted to contribute to proton-transporting ATPase activity, rotational mechanism. Involved in terminal branching, open tracheal system and vacuolar acidification. Located in plasma membrane. Part of plasma membrane proton-transporting V-type ATPase complex. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; ganglia; gut section; and somatic precursor cell. Orthologous to several human genes including ATP6V0D1 (ATPase H+ transporting V0 subunit d1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (3880748..3882967)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (3774781..3777000)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to proton-transporting ATPase activity, rotational mechanism	IC Inferred by Curator more info	PubMed
enables proton-transporting ATPase activity, rotational mechanism	IEA Inferred from Electronic Annotation more info
contributes_to proton-transporting ATPase activity, rotational mechanism	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to increased oxygen levels	ISS Inferred from Sequence or Structural Similarity more info
involved_in intracellular iron ion homeostasis	ISS Inferred from Sequence or Structural Similarity more info
involved_in proton transmembrane transport	IC Inferred by Curator more info	PubMed
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in terminal branching, open tracheal system	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in vacuolar acidification	IBA Inferred from Biological aspect of Ancestor more info
involved_in vacuolar acidification	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in vacuolar transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in early endosome	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	HDA more info	PubMed
part_of plasma membrane proton-transporting V-type ATPase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of plasma membrane proton-transporting V-type ATPase complex	IMP Inferred from Mutant Phenotype more info	PubMed
part_of proton-transporting V-type ATPase, V0 domain	IEA Inferred from Electronic Annotation more info
part_of vacuolar proton-transporting V-type ATPase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of vacuolar proton-transporting V-type ATPase, V0 domain	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Names: CG2934-PA; V-ATPase V0 d subunit; VhaAC39; VhaAC39-1-PA; chocolate; vacuolar ATPsintase subunit 1; vacuolar H[+] ATPase subunit AC39-1; vacuolar H[+]-ATPase C39 subunit

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The following sections contain reference sequences that belong to a specific genome build. Explain