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    nom numerous disordered muscles [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41038, updated on 17-Dec-2024

    Summary

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    Official Symbol
    nomprovided by FlyBase
    Official Full Name
    numerous disordered musclesprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037617
    Locus tag
    Dmel_CG8145
    See related
    AllianceGenome:FB:FBgn0037617
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8145; Dmel\CG8145; Sean
    Summary
    Enables DNA binding activity. Involved in larval somatic muscle development. Predicted to be located in nucleus. Is expressed in embryonic/larval fat body; organism; and ring gland primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See nom in Genome Data Viewer
    Location:
    85A9-85A9; 3-48 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8723174..8725357)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4548896..4551079)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Transmembrane protein 216 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ouija board Neighboring gene uncharacterized protein Neighboring gene ranshi

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Study of the Association of Ouib and Nom with Heterochromatin in Drosophila melanogaster. Pekina YV, et al. Dokl Biochem Biophys, 2023 Dec. PMID 38472665
    2. Cooperative Control of Ecdysone Biosynthesis in Drosophila by Transcription Factors Séance, Ouija Board, and Molting Defective. Uryu O, et al. Genetics, 2018 Feb. PMID 29187506, Free PMC Article
    3. Whole-genome analysis of muscle founder cells implicates the chromatin regulator Sin3A in muscle identity. Dobi KC, et al. Cell Rep, 2014 Aug 7. PMID 25088419, Free PMC Article
    4. Soul is a master control gene governing the development of the Drosophila prothoracic gland. Liu W, et al. Proc Natl Acad Sci U S A, 2024 Oct. PMID 39312662,
    5. Global analysis of target genes of 21 members of the ZAD transcription factor family in Drosophila melanogaster. Krystel J, et al. Gene, 2013 Jan 10. PMID 23085320, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Study of the Association of Ouib and Nom with Heterochromatin in Drosophila melanogaster.
      Title: Study of the Association of Ouib and Nom with Heterochromatin in Drosophila melanogaster.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in larval somatic muscle development IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in larval somatic muscle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    numerous disordered muscles
    Names
    CG8145-PA
    CG8145-PB
    CG8145-PC
    nom-PA
    nom-PB
    nom-PC
    seance

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8723174..8725357
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300312.1 → NP_001287241.1  numerous disordered muscles, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287241.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MT86, Q9VHM7
      Conserved Domains (3) summary
      smart00868
      Location:5 → 76
      zf-AD; Zinc-finger associated domain (zf-AD)
      sd00017
      Location:184 → 204
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:255 → 278
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001275455.1 → NP_001262384.1  numerous disordered muscles, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262384.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MT86, Q9VHM7
      Conserved Domains (3) summary
      smart00868
      Location:5 → 76
      zf-AD; Zinc-finger associated domain (zf-AD)
      sd00017
      Location:184 → 204
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:255 → 278
      zf-H2C2_2; Zinc-finger double domain

    3. NM_141564.4 → NP_649821.2  numerous disordered muscles, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649821.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MT86, Q9VHM7
      Related
      FBpp0081394
      Conserved Domains (3) summary
      smart00868
      Location:5 → 76
      zf-AD; Zinc-finger associated domain (zf-AD)
      sd00017
      Location:184 → 204
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:255 → 278
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MSE5 Q8MSE5
    Q8MT86 Q8MT86
    Q9VHM7 Q9VHM7

    Gene LinkOut

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