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    Cyp28d1 Cytochrome P450 28d1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33749, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cyp28d1provided by FlyBase
    Official Full Name
    Cytochrome P450 28d1provided by FlyBase
    Primary source
    FLYBASE:FBgn0031689
    Locus tag
    Dmel_CG10833
    See related
    AllianceGenome:FB:FBgn0031689
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    28d1; CG10833; CYP28d1; Dmel\CG10833
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in several structures, including adult head; embryonic/larval midgut; and epithelial tube. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cyp28d1 in Genome Data Viewer
    Location:
    25C10-25C10; 2-15 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5210460..5212445)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5210460..5212445)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Muscle-specific protein 300 kDa Neighboring gene small non-coding RNA 158 Neighboring gene Cytochrome P450 28d2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Troponin C at 25D Neighboring gene thickveins

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dynamics and stage-specificity of between-population gene expression divergence in the Drosophila melanogaster larval fat body. Glaser-Schmitt A, et al. PLoS Genet, 2023 Apr. PMID 37099612, Free PMC Article
    2. Naturally Segregating Variation at Ugt86Dd Contributes to Nicotine Resistance in Drosophila melanogaster. Highfill CA, et al. Genetics, 2017 Sep. PMID 28743761, Free PMC Article
    3. Selenoprotein dSelK in Drosophila elevates release of Ca2+ from endoplasmic reticulum by upregulating expression of inositol 1,4,5-tris-phosphate receptor. Ben SB, et al. Biochemistry (Mosc), 2011 Sep. PMID 22082272
    4. Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits. Chakraborty M, et al. Nat Commun, 2019 Oct 25. PMID 31653862, Free PMC Article
    5. Alkaline Ceramidase Mediates the Oxidative Stress Response in Drosophila melanogaster Through Sphingosine. Zhang CH, et al. J Insect Sci, 2019 May 1. PMID 31115476, Free PMC Article

    See all (59) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450 28d1
    Names
    CG10833-PA
    Cyp28d1-PA
    cytochrome P450
    NP_608912.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5210460..5212445
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135068.4 → NP_608912.1  cytochrome P450 28d1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608912.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VMT5
      Related
      FBpp0078698
      Conserved Domains (1) summary
      pfam00067
      Location:35 → 477
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VMT5.1 Q9VMT5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
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