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    CAH16 Carbonic anhydrase 16 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50101, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CAH16provided by FlyBase
    Official Full Name
    Carbonic anhydrase 16provided by FlyBase
    Primary source
    FLYBASE:FBgn0040628
    Locus tag
    Dmel_CG18672
    See related
    AllianceGenome:FB:FBgn0040628
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG18672; Dmel\CG18672
    Summary
    Predicted to enable carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be active in cytoplasm. Orthologous to human CA6 (carbonic anhydrase 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CAH16 in Genome Data Viewer
    Location:
    100B9-100B9; 3-102 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31260247..31261667)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27085969..27087389)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene spn-F Neighboring gene Carbonic anhydrase 6 Neighboring gene Carbonic anhydrase 5 Neighboring gene pickpocket 24

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Carbonic anhydrases and anion transport in mosquito midgut pH regulation. Linser PJ, et al. J Exp Biol, 2009 Jun. PMID 19448076, Free PMC Article
    2. Single-nucleus transcriptomes reveal evolutionary and functional properties of cell types in the Drosophila accessory gland. Majane AC, et al. Genetics, 2022 Feb 4. PMID 34849871, Free PMC Article
    3. Research gaps and new insights in the evolution of Drosophila seminal fluid proteins. Hurtado J, et al. Insect Mol Biol, 2022 Apr. PMID 34747062
    4. The genetic basis for variation in resistance to infection in the Drosophila melanogaster genetic reference panel. Wang JB, et al. PLoS Pathog, 2017 Mar. PMID 28257468, Free PMC Article
    5. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbonate dehydratase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbonate dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    carbonic anhydrase 16
    Names
    CAH16-PB
    CAH16-PC
    CAH16-PD
    CG18672-PB
    CG18672-PC
    CG18672-PD
    NP_001287620.1
    NP_001287621.1
    NP_652276.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      31260247..31261667
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300691.1 → NP_001287620.1  carbonic anhydrase 16, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287620.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LHX0
      Conserved Domains (1) summary
      smart01057
      Location:26 → 278
      Carb_anhydrase; Eukaryotic-type carbonic anhydrase

    2. NM_144019.2 → NP_652276.2  carbonic anhydrase 16, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652276.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B9ER07, Q9V9Y7
      Conserved Domains (1) summary
      smart01057
      Location:26 → 276
      Carb_anhydrase; Eukaryotic-type carbonic anhydrase

    3. NM_001300692.1 → NP_001287621.1  carbonic anhydrase 16, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287621.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LHX8
      Conserved Domains (1) summary
      smart01057
      Location:26 → 273
      Carb_anhydrase; Eukaryotic-type carbonic anhydrase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LHX0 A0A0B4LHX0
    A0A0B4LHX8 A0A0B4LHX8
    Q9V9Y7 Q9V9Y7

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