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    Kif3C Kinesin family member 3C [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43820, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Kif3Cprovided by FlyBase
    Official Full Name
    Kinesin family member 3Cprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039925
    Locus tag
    Dmel_CG17461
    See related
    AllianceGenome:FB:FBgn0039925
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17459; CG17461; CP38609; Dmel\CG17461; DmKif3C; DmKIF3C; KIF 24; KIF 3C; KIF17; Kif3c; KIF3C; KIF3Cdm
    Summary
    Predicted to enable ATP hydrolysis activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Predicted to be involved in anterograde dendritic transport of neurotransmitter receptor complex and cell projection organization. Predicted to be part of kinesin complex. Predicted to be active in several cellular components, including cilium; microtubule cytoskeleton; and neuron projection. Orthologous to human KIF17 (kinesin family member 17). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Kif3C in Genome Data Viewer
    Location:
    102F8-102F8; 4-0 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 4 NC_004353.4 (1147466..1169239)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 4 NC_004353.3 (1168092..1189865)

    Chromosome 4 - NC_004353.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ADP ribosylation factor 4 Neighboring gene uncharacterized protein Neighboring gene pleiohomeotic Neighboring gene uncharacterized protein Neighboring gene Phosphatidylinositol 5-phosphate 4-kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Kinesin and dynein move a peroxisome in vivo: a tug-of-war or coordinated movement? Kural C, et al. Science, 2005 Jun 3. PMID 15817813
    2. Msps governs acentrosomal microtubule assembly and reactivation of quiescent neural stem cells. Deng Q, et al. EMBO J, 2021 Oct 1. PMID 34368973, Free PMC Article
    3. Effect of spaceflight on the circadian rhythm, lifespan and gene expression of Drosophila melanogaster. Ma L, et al. PLoS One, 2015. PMID 25798821, Free PMC Article
    4. Comparative transcriptomics between Drosophila mojavensis and D. arizonae reveals transgressive gene expression and underexpression of spermatogenesis-related genes in hybrid testes. Banho CA, et al. Sci Rep, 2021 May 10. PMID 33972659, Free PMC Article
    5. A new kinesin tree. Dagenbach EM, et al. J Cell Sci, 2004 Jan 1. PMID 14657268

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: 1148453-1148589 mobile_element_type = transposon:INE-1{}3958
    • Loc: 1149540-1149875 mobile_element_type = transposon:gypsy2{}4593
    • Loc: 1167772-1168903 mobile_element_type = transposon:1360{}1558

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables minus-end-directed microtubule motor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables plus-end-directed microtubule motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in anterograde dendritic transport of neurotransmitter receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell projection organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of kinesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    kinesin family member 3C
    Names
    CG17461-PA
    Kif3C-PA
    Kinesin2C
    kinesin family member 3C ortholog
    kinesin superfamily protein 3C
    NP_651939.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004353.4 Reference assembly

      Range
      1147466..1169239
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143682.4 → NP_651939.4  kinesin family member 3C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651939.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NNT2, Q9V4A1
      Conserved Domains (2) summary
      cl22853
      Location:3 → 339
      Motor_domain; Myosin and Kinesin motor domain
      pfam00225
      Location:10 → 339
      Kinesin; Kinesin motor domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V4A1 Q9V4A1

    Gene LinkOut

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