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    Vm26Ab Vitelline membrane 26Ab [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33827, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vm26Abprovided by FlyBase
    Official Full Name
    Vitelline membrane 26Abprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003980
    Locus tag
    Dmel_CG9046
    See related
    AllianceGenome:FB:FBgn0003980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9046; DIM 29; Dm sV23; Dmel\CG9046; fs(2)QJ42; sv23; sV23; Sv23; sV26; TU-4; Vm26A; VM26A.2; VM26AB
    Summary
    Involved in egg activation and vitelline membrane formation involved in chorion-containing eggshell formation. Located in vitelline envelope. Is expressed in follicle cell; main body follicle cell; and vitelline membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Vm26Ab in Genome Data Viewer
    Location:
    26A3-26A3; 2-18 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5957004..5957639)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5957004..5957639)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Vitelline membrane 26Aac Neighboring gene Vitelline membrane 26Aa

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular analysis and rescue of a vitelline membrane mutant in Drosophila. Savant SS, et al. Dev Biol, 1989 Sep. PMID 2504634
    2. Isolation of two Drosophila melanogaster genes abundantly expressed in the ovary during vitelline membrane synthesis. Higgins MJ, et al. Dev Biol, 1984 Sep. PMID 6088330
    3. Ovulation triggers activation of Drosophila oocytes. Heifetz Y, et al. Dev Biol, 2001 Jun 15. PMID 11397010
    4. The Drosophila drop-dead gene is required for eggshell integrity. Sheahan TD, et al. PLoS One, 2023. PMID 38051756, Free PMC Article
    5. The N-terminal prodomain of sV23 is essential for the assembly of a functional vitelline membrane network in Drosophila. Manogaran A, et al. Dev Biol, 2004 Jun 1. PMID 15136154

    See all (66) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in chorion-containing eggshell formation HMP PubMed 
    involved_in egg activation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to bacterium HEP PubMed 
    involved_in vitelline membrane formation involved in chorion-containing eggshell formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in vitelline envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in vitelline envelope IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vitelline membrane 26Ab
    Names
    CG9046-PA
    CG9046-PB
    Vm26Ab-PA
    Vm26Ab-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5957004..5957639
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298719.1 → NP_001285648.1  vitelline membrane 26Ab, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285648.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4UM08, P13238, Q9VMK6
      UniProtKB/TrEMBL
      A8E794, X2J4V0
      Conserved Domains (1) summary
      pfam10542
      Location:118 → 154
      Vitelline_membr; Vitelline membrane cysteine-rich region

    2. NM_057436.2 → NP_476784.1  vitelline membrane 26Ab, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476784.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4UM08, P13238, Q9VMK6
      UniProtKB/TrEMBL
      A8E794, X2J4V0
      Related
      FBpp0078802, FBtr0079171
      Conserved Domains (1) summary
      pfam10542
      Location:118 → 154
      Vitelline_membr; Vitelline membrane cysteine-rich region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P13238.2 P13238
    X2J4V0 X2J4V0

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