aft adrift [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: aftprovided by FlyBase
Official Full Name: adriftprovided by FlyBase
Primary source: FLYBASE:FBgn0026309
Locus tag: Dmel_CG5032
See related: AllianceGenome:FB:FBgn0026309
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG5032; CMTr2; Dmel\CG5032; EG:52C10.7
Summary: Enables mRNA (nucleoside-2'-O-)-methyltransferase activity. Involved in 7-methylguanosine mRNA capping and open tracheal system development. Located in nucleus. Is expressed in several structures, including epithelium; larval tracheal system; primary segmental tracheal branch primordium; supraesophageal ganglion; and tracheal tip cell. Orthologous to human CMTR2 (cap methyltransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (17786135..17788556)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (13673640..13676061)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables mRNA (nucleoside-2'-O-)-methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables mRNA (nucleoside-2'-O-)-methyltransferase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables mRNA (nucleoside-2'-O-)-methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in 7-methylguanosine mRNA capping	IBA Inferred from Biological aspect of Ancestor more info
involved_in 7-methylguanosine mRNA capping	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in methylation	IEA Inferred from Electronic Annotation more info
involved_in open tracheal system development	IEP Inferred from Expression Pattern more info	PubMed
involved_in open tracheal system development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of positive regulation of intracellular mRNA localization	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	TAS Traceable Author Statement more info	PubMed