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    Amino acid dehydrogenase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818448, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Amino acid dehydrogenase family protein
    Primary source
    TAIR:AT2G38660
    Locus tag
    AT2G38660
    See related
    Araport:AT2G38660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T6A23.14; T6A23_14
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (16165921..16168628)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene galacturonosyltransferase 7 Neighboring gene phosphorylethanolamine cytidylyltransferase 1 Neighboring gene 5'-nucleotidase / magnesium ion binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036431.3
    NM_001125000.3
    NM_001202774.1
    NM_001336715.1
    NM_001336716.1
    NM_001336717.1
    NM_001336718.1
    NM_129423.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables methenyltetrahydrofolate cyclohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in tetrahydrofolate interconversion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Amino acid dehydrogenase family protein
    NP_001031508.1
    • Amino acid dehydrogenase family protein; FUNCTIONS IN: binding, catalytic activity; INVOLVED IN: folic acid and derivative biosynthetic process, metabolic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain (InterPro:IPR020631), Tetrahydrofolate dehydrogenase/cyclohydrolase (InterPro:IPR000672), NAD(P)-binding domain (InterPro:IPR016040), Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain (InterPro:IPR020630); BEST Arabidopsis thaliana protein match is: Amino acid dehydrogenase family protein (TAIR:AT4G00620.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001118472.1
    • Amino acid dehydrogenase family protein; FUNCTIONS IN: binding, catalytic activity; INVOLVED IN: folic acid and derivative biosynthetic process, metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain (InterPro:IPR020631), Tetrahydrofolate dehydrogenase/cyclohydrolase (InterPro:IPR000672), NAD(P)-binding domain (InterPro:IPR016040), Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site (InterPro:IPR020867), Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain (InterPro:IPR020630); BEST Arabidopsis thaliana protein match is: Amino acid dehydrogenase family protein (TAIR:AT4G00620.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001189703.1
    • Amino acid dehydrogenase family protein; FUNCTIONS IN: binding, catalytic activity; INVOLVED IN: folic acid and derivative biosynthetic process, metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain (InterPro:IPR020631), Tetrahydrofolate dehydrogenase/cyclohydrolase (InterPro:IPR000672), NAD(P)-binding domain (InterPro:IPR016040), Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain (InterPro:IPR020630); BEST Arabidopsis thaliana protein match is: Amino acid dehydrogenase family protein (TAIR:AT4G00620.1).
    NP_181400.2
    • Amino acid dehydrogenase family protein; FUNCTIONS IN: binding, catalytic activity; INVOLVED IN: folic acid and derivative biosynthetic process, metabolic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain (InterPro:IPR020631), Tetrahydrofolate dehydrogenase/cyclohydrolase (InterPro:IPR000672), NAD(P)-binding domain (InterPro:IPR016040), Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site (InterPro:IPR020867), Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain (InterPro:IPR020630); BEST Arabidopsis thaliana protein match is: Amino acid dehydrogenase family protein (TAIR:AT4G00620.1); Has 9936 Blast hits to 9931 proteins in 2768 species: Archae - 105; Bacteria - 5635; Metazoa - 391; Fungi - 308; Plants - 157; Viruses - 0; Other Eukaryotes - 3340 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      16165921..16168628
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001125000.3 → NP_001118472.1  Amino acid dehydrogenase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001118472.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A2RVV7, C0Z3J6, F4ITV6, Q84W19, Q9ZVI8
      UniProtKB/TrEMBL
      A0A7G2ECL2
      Conserved Domains (3) summary
      cd01080
      Location:177 → 348
      NAD_bind_m-THF_DH_Cyclohyd; NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase
      PLN02897
      Location:8 → 352
      PLN02897; tetrahydrofolate dehydrogenase/cyclohydrolase, putative
      pfam00763
      Location:65 → 181
      THF_DHG_CYH; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain

    2. NM_129423.6 → NP_181400.2  Amino acid dehydrogenase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181400.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A2RVV7, C0Z3J6, F4ITV6, Q84W19, Q9ZVI8
      UniProtKB/TrEMBL
      A0A7G2ECL2
      Conserved Domains (3) summary
      cd01080
      Location:177 → 348
      NAD_bind_m-THF_DH_Cyclohyd; NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase
      PLN02897
      Location:8 → 352
      PLN02897; tetrahydrofolate dehydrogenase/cyclohydrolase, putative
      pfam00763
      Location:65 → 181
      THF_DHG_CYH; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain

    3. NM_001336715.1 → NP_001324647.1  Amino acid dehydrogenase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VVJ5

    4. NM_001336716.1 → NP_001324644.1  Amino acid dehydrogenase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VVJ5

    5. NM_001336717.1 → NP_001324645.1  Amino acid dehydrogenase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VVJ5

    6. NM_001336718.1 → NP_001324646.1  Amino acid dehydrogenase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VVJ5

    7. NM_001036431.3 → NP_001031508.1  Amino acid dehydrogenase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031508.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A2RVV7
      Conserved Domains (2) summary
      pfam00763
      Location:65 → 181
      THF_DHG_CYH; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
      cl21454
      Location:177 → 243
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    8. NM_001202774.1 → NP_001189703.1  Amino acid dehydrogenase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189703.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2ECL2
      Conserved Domains (2) summary
      cd01080
      Location:177 → 317
      NAD_bind_m-THF_DH_Cyclohyd; NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase
      pfam00763
      Location:65 → 181
      THF_DHG_CYH; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2RVV7.1

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