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    LOS1 Ribosomal protein S5/Elongation factor G/III/V family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842058, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LOS1
    Official Full Name
    Ribosomal protein S5/Elongation factor G/III/V family protein
    Primary source
    TAIR:AT1G56070
    Locus tag
    AT1G56070
    See related
    Araport:AT1G56070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AT1G56075; AT1G56075.1; LOW EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1; T6H22.13; T6H22.24; T6H22_13
    Summary
    encodes a translation elongation factor 2-like protein that is involved in cold-induced translation. Mutations in this gene specifically blocks low temperature-induced transcription of cold-responsive genes but induces the expression of CBF genes and mutants carrying the recessive mutations fail to acclimate to cold and is freezing sensitive.
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    Genomic context

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    See LOS1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (20967652..20971742, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene GTP-binding protein-like protein Neighboring gene cysteine-rich/transmembrane domain protein B Neighboring gene interactor of constitutive active ROPs protein Neighboring gene Cyclophilin Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic analysis of osmotic and cold stress signal transduction in Arabidopsis: interactions and convergence of abscisic acid-dependent and abscisic acid-independent pathways. Ishitani M, et al. Plant Cell, 1997 Nov. PMID 9401119, Free PMC Article
    2. An Arabidopsis mutation in translation elongation factor 2 causes superinduction of CBF/DREB1 transcription factor genes but blocks the induction of their downstream targets under low temperatures. Guo Y, et al. Proc Natl Acad Sci U S A, 2002 May 28. PMID 12032361, Free PMC Article
    3. Proteomic survey of copper-binding proteins in Arabidopsis roots by immobilized metal affinity chromatography and mass spectrometry. Kung CC, et al. Proteomics, 2006 May. PMID 16526091
    4. The Arabidopsis metacaspase9 degradome. Tsiatsiani L, et al. Plant Cell, 2013 Aug. PMID 23964026, Free PMC Article
    5. Tandem affinity purification and mass spectrometric analysis of ubiquitylated proteins in Arabidopsis. Saracco SA, et al. Plant J, 2009 Jul. PMID 19292762, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001333759.1
    NM_001333760.1
    NM_179487.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables copper ion binding HDA PubMed 
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cold acclimation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translational elongation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    NOT located_in Golgi apparatus RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in chloroplast HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in nucleolus HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    Ribosomal protein S5/Elongation factor G/III/V family protein
    NP_849818.1
    • LOW EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1 (LOS1); FUNCTIONS IN: translation factor activity, nucleic acid binding, copper ion binding, translation elongation factor activity; INVOLVED IN: response to cold; LOCATED IN: cytosol, nucleolus, chloroplast, plasma membrane, membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein synthesis factor, GTP-binding (InterPro:IPR000795), Translation elongation factor EFG/EF2, domain IV (InterPro:IPR005517), Translation elongation factor EFG/EF2, C-terminal (InterPro:IPR000640), Translation elongation factor EFTu/EF1A, domain 2 (InterPro:IPR004161), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), Elongation factor G/III/V (InterPro:IPR009022), Translation elongation/initiation factor/Ribosomal, beta-barrel (InterPro:IPR009000); BEST Arabidopsis thaliana protein match is: Ribosomal protein S5/Elongation factor G/III/V family protein (TAIR:AT3G12915.1); Has 64297 Blast hits to 57476 proteins in 4618 species: Archae - 1324; Bacteria - 41101; Metazoa - 3172; Fungi - 1934; Plants - 1269; Viruses - 1; Other Eukaryotes - 15496 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20967652..20971742 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179487.2 → NP_849818.1  Ribosomal protein S5/Elongation factor G/III/V family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849818.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z355, Q56WX9, Q56WY3, Q570K2, Q84R07, Q8H145, Q94CA4, Q9ASR1, Q9SGT4
      UniProtKB/TrEMBL
      A0A178WBS0, A0A5S9WMT1, F4JNE0
      Conserved Domains (1) summary
      PLN00116
      Location:1 → 843
      PLN00116; translation elongation factor EF-2 subunit; Provisional

    2. NM_001333759.1 → NP_001321033.1  Ribosomal protein S5/Elongation factor G/III/V family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z355, Q56WX9, Q56WY3, Q570K2, Q84R07, Q8H145, Q94CA4, Q9ASR1, Q9SGT4
      UniProtKB/TrEMBL
      A0A178WBS0, A0A5S9WMT1, F4JNE0
      Conserved Domains (1) summary
      PLN00116
      Location:1 → 843
      PLN00116; translation elongation factor EF-2 subunit; Provisional

    3. NM_001333760.1 → NP_001321034.1  Ribosomal protein S5/Elongation factor G/III/V family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z355, Q56WX9, Q56WY3, Q570K2, Q84R07, Q8H145, Q94CA4, Q9ASR1, Q9SGT4
      UniProtKB/TrEMBL
      A0A178WBS0, A0A5S9WMT1, F4JNE0
      Conserved Domains (1) summary
      PLN00116
      Location:1 → 843
      PLN00116; translation elongation factor EF-2 subunit; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ASR1.1

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