ASPGB1 N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ASPGB1
Official Full Name: N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein
Primary source: TAIR:AT3G16150
Locus tag: AT3G16150
See related: Araport:AT3G16150
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: asparaginase B1
Summary: Encodes an asparaginase that catalyzes the degradation of L-asparagine to L-aspartic acid and ammonia.
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Genomic context

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See ASPGB1 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 4

Sequence:: Chromosome: 3; NC_003074.8 (5471735..5473360)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

At3g16150 encodes a K+-dependent L-asparaginase with expression levels highest in sink tissues, especially in flowers and siliques, early in development.
Title: Co-occurrence of both L-asparaginase subtypes in Arabidopsis: At3g16150 encodes a K+-dependent L-asparaginase.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_112485.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables asparaginase activity	IDA Inferred from Direct Assay more info	PubMed
enables beta-aspartyl-peptidase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein

NP_566536.1

N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein; CONTAINS InterPro DOMAIN/s: Peptidase T2, asparaginase 2 (InterPro:IPR000246); BEST Arabidopsis thaliana protein match is: N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein (TAIR:AT5G08100.1); Has 3285 Blast hits to 3219 proteins in 891 species: Archae - 113; Bacteria - 1512; Metazoa - 512; Fungi - 247; Plants - 200; Viruses - 0; Other Eukaryotes - 701 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

5471735..5473360

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_112485.4 → NP_566536.1 N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_566536.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8GXG1, Q9LW72

UniProtKB/TrEMBL

A0A178VDS2, A0A384KV24, Q29Q32

Conserved Domains (1) summary

PLN02689
Location:1 → 325

PLN02689; Bifunctional isoaspartyl peptidase/L-asparaginase