DOT5 C2H2-like zinc finger protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: DOT5
Official Full Name: C2H2-like zinc finger protein
Primary source: TAIR:AT1G13290
Locus tag: AT1G13290
See related: Araport:AT1G13290
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: DEFECTIVELY ORGANIZED TRIBUTARIES 5; T6J4.5; T6J4_5; WIP domain protein 6; WIP6
Summary: Encodes a putative zinc finger protein (C2H2 family, type IIIA, subclass A1d) that has a WIP domain. Seedlings with mutations in DOT5 have a misaligned venation defect in their leaves and cotyledons. Additional developmental abnormalities, such as elongated petioles and aberrant phyllotaxy suggest that DOT5 is required for normal shoot and root development.
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Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

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NM_101200.2

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cotyledon vascular tissue pattern formation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within leaf vascular tissue pattern formation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within phloem or xylem histogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within root development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within shoot system development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

NP_172787.1

DEFECTIVELY ORGANIZED TRIBUTARIES 5 (DOT5); CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Zinc finger, C2H2-type (InterPro:IPR007087); BEST Arabidopsis thaliana protein match is: C2H2-type zinc finger family protein (TAIR:AT3G57670.1); Has 7460 Blast hits to 6100 proteins in 157 species: Archae - 0; Bacteria - 0; Metazoa - 6553; Fungi - 59; Plants - 690; Viruses - 0; Other Eukaryotes - 158 (source: NCBI BLink).