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    RGF4 root meristem growth factor-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822736, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RGF4
    Official Full Name
    root meristem growth factor-like protein
    Primary source
    TAIR:AT3G30350
    Locus tag
    AT3G30350
    See related
    Araport:AT3G30350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    GLV3; GOLVEN 3; root meristem growth factor 4
    Summary
    Encodes a root meristem growth factor (RGF). Belongs to a family of functionally redundant homologous peptides that are secreted, tyrosine-sulfated, and expressed mainly in the stem cell area and the innermost layer of central columella cells. RGFs are required for maintenance of the root stem cell niche and transit amplifying cell proliferation. Members of this family include: At5g60810 (RGF1), At1g13620 (RGF2), At2g04025 (RGF3), At3g30350 (RGF4), At5g51451 (RGF5), At4g16515 (RGF6), At3g02240 (RGF7), At2g03830 (RGF8) and At5g64770 (RGF9).
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    Genomic context

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    See RGF4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (11960298..11961917, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene nodulin MtN21 /EamA-like transporter family protein Neighboring gene tRNA-Lys Neighboring gene pseudo Neighboring gene MuDR family transposase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GOLVEN secretory peptides regulate auxin carrier turnover during plant gravitropic responses. Whitford R, et al. Dev Cell, 2012 Mar 13. PMID 22421050
    2. Secreted peptide signals required for maintenance of root stem cell niche in Arabidopsis. Matsuzaki Y, et al. Science, 2010 Aug 27. PMID 20798316
    3. Identification of three LRR-RKs involved in perception of root meristem growth factor in Arabidopsis. Shinohara H, et al. Proc Natl Acad Sci U S A, 2016 Apr 5. PMID 27001831, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001339050.1
    NM_113934.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables growth factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables hormone activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive gravitropism IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive gravitropism IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of auxin polar transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of protein localization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    root meristem growth factor-like protein
    NP_001319668.1
    • root meristem growth factor 4 (RGF4); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; EXPRESSED IN: hypocotyl, root.
    NP_566853.1
    • root meristem growth factor 4 (RGF4); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; EXPRESSED IN: hypocotyl, root; Has 4 Blast hits to 4 proteins in 2 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 4; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      11960298..11961917 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113934.3 → NP_566853.1  root meristem growth factor-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566853.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L8Q0, Q9LI64
      UniProtKB/TrEMBL
      A0A7G2EQI9

    2. NM_001339050.1 → NP_001319668.1  root meristem growth factor-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EQI9, F4J5G8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LI64.2

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