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    PRR2 pinoresinol reductase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827000, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PRR2
    Official Full Name
    pinoresinol reductase 2
    Primary source
    TAIR:AT4G13660
    Locus tag
    AT4G13660
    See related
    Araport:AT4G13660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPRR2; F18A5.50; F18A5_50; pinoresinol reductase 2; PSEUDO-RESPONSE REGULATOR 2
    Summary
    Encodes a pinoresinol reductase involved in lignan biosynthesis. Expressed strongly in roots and less strongly in stems. Shows preference for pinoresinol and not lariciresinol.
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    Genomic context

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    See PRR2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (7945683..7948443)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene miscRNA Neighboring gene plastid transcriptionally active 5 Neighboring gene hypothetical protein (DUF295)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PRR2, a pseudo-response regulator, promotes salicylic acid and camalexin accumulation during plant immunity. Cheval C, et al. Sci Rep, 2017 Aug 1. PMID 28765536, Free PMC Article
    2. Characterization of Arabidopsis thaliana pinoresinol reductase, a new type of enzyme involved in lignan biosynthesis. Nakatsubo T, et al. J Biol Chem, 2008 Jun 6. PMID 18347017, Free PMC Article
    3. Evolution of plant defense mechanisms. Relationships of phenylcoumaran benzylic ether reductases to pinoresinol-lariciresinol and isoflavone reductases. Gang DR, et al. J Biol Chem, 1999 Mar 12. PMID 10066819
    4. Interaction of a plant pseudo-response regulator with a calmodulin-like protein. Perochon A, et al. Biochem Biophys Res Commun, 2010 Aug 6. PMID 20627089
    5. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001340871.1
    NM_117440.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables pinoresinol reductase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pinoresinol reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within lignan biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    pinoresinol reductase 2
    NP_001319922.1
    • pinoresinol reductase 2 (PRR2); CONTAINS InterPro DOMAIN/s: NAD(P)-binding domain (InterPro:IPR016040), NmrA-like (InterPro:IPR008030); BEST Arabidopsis thaliana protein match is: pinoresinol reductase 1 (TAIR:AT1G32100.1); Has 1530 Blast hits to 1530 proteins in 324 species: Archae - 16; Bacteria - 400; Metazoa - 3; Fungi - 451; Plants - 554; Viruses - 0; Other Eukaryotes - 106 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      7945683..7948443
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001340871.1 → NP_001319922.1  pinoresinol reductase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SVP6
      UniProtKB/TrEMBL
      A0A5S9XST2
      Conserved Domains (1) summary
      cd05259
      Location:11 → 312
      PCBER_SDR_a; phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs

    2. NM_117440.3 → NP_193102.1  pinoresinol reductase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193102.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SVP6
      UniProtKB/TrEMBL
      A0A5S9XST2
      Conserved Domains (1) summary
      cd05259
      Location:11 → 312
      PCBER_SDR_a; phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SVP6.1

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