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    GLN1;4 glutamine synthetase 1;4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831519, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GLN1;4
    Official Full Name
    glutamine synthetase 1;4
    Primary source
    TAIR:AT5G16570
    Locus tag
    AT5G16570
    See related
    Araport:AT5G16570
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    glutamine synthetase 1;4; MTG13.1
    Summary
    Encodes a cytosolic glutamine synthetase, the enzyme has high affinity with substrate ammonium
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    Genomic context

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    See GLN1;4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Sequence:
    Chromosome: 5; NC_003076.8 (5421589..5424749, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene voltage-dependent L-type calcium channel subunit Neighboring gene Homeodomain-like superfamily protein Neighboring gene ncRNA Neighboring gene beta glucosidase 2 Neighboring gene Leucine-rich repeat protein kinase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Kinetic properties and ammonium-dependent regulation of cytosolic isoenzymes of glutamine synthetase in Arabidopsis. Ishiyama K, et al. J Biol Chem, 2004 Apr 16. PMID 14757761
    2. Gln49 and Ser174 residues play critical roles in determining the catalytic efficiencies of plant glutamine synthetase. Ishiyama K, et al. Plant Cell Physiol, 2006 Feb. PMID 16338958
    3. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    4. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    NM_121663.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glutamine synthetase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glutamine synthetase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutamine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within nitrate assimilation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    glutamine synthetase 1;4
    NP_568335.1
    • glutamine synthetase 1;4 (GLN1;4); CONTAINS InterPro DOMAIN/s: Glutamine synthetase, catalytic domain (InterPro:IPR008146), Glutamine synthetase, beta-Grasp (InterPro:IPR008147), Glutamine synthetase/guanido kinase, catalytic domain (InterPro:IPR014746); BEST Arabidopsis thaliana protein match is: glutamine synthase clone R1 (TAIR:AT5G37600.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5421589..5424749 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343456.1 → NP_001331815.1  glutamine synthetase 1;4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BF22
      Conserved Domains (1) summary
      PLN02284
      Location:1 → 240
      PLN02284; glutamine synthetase

    2. NM_121663.3 → NP_568335.1  glutamine synthetase 1;4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568335.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FMD9
      UniProtKB/TrEMBL
      A0A178UB24, A0A5S9Y531
      Conserved Domains (1) summary
      PLN02284
      Location:1 → 354
      PLN02284; glutamine synthetase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FMD9.1

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