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    CYP96A15 cytochrome P450, family 96, subfamily A, polypeptide 15 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842150, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYP96A15
    Official Full Name
    cytochrome P450, family 96, subfamily A, polypeptide 15
    Primary source
    TAIR:AT1G57750
    Locus tag
    AT1G57750
    See related
    Araport:AT1G57750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''cytochrome P450; cytochrome P450; family 96; MAH1; MID-CHAIN ALKANE HYDROXYLASE 1; polypeptide 15; polypeptide 15''; subfamily A; T8L23.21; T8L23_21
    Summary
    Encodes a CYP96A15, midchain alkane hydroxylase, involved in cuticular wax biosynthesis.
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    Genomic context

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    See CYP96A15 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (21383812..21385709, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene miscRNA Neighboring gene ECA1 gametogenesis family protein (DUF784) Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The cytochrome P450 enzyme CYP96A15 is the midchain alkane hydroxylase responsible for formation of secondary alcohols and ketones in stem cuticular wax of Arabidopsis. Greer S, et al. Plant Physiol, 2007 Nov. PMID 17905869, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A reverse-genetic approach was used to identify a cytochrome P450 enzyme (CYP96A15) involved in wax biosynthesis and characterized it as a midchain alkane hydroxylase.
      Title: The cytochrome P450 enzyme CYP96A15 is the midchain alkane hydroxylase responsible for formation of secondary alcohols and ketones in stem cuticular wax of Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_001124037.1
    NM_104570.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables midchain alkane hydroxylase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within wax biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450, family 96, subfamily A, polypeptide 15
    NP_001117509.1
    • ''cytochrome P450, family 96, subfamily A, polypeptide 15'' (CYP96A15); CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 96, subfamily A, polypeptide 3 (TAIR:AT1G65340.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_176086.1
    • ''cytochrome P450, family 96, subfamily A, polypeptide 15'' (CYP96A15); CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 96, subfamily A, polypeptide 3 (TAIR:AT1G65340.1); Has 29548 Blast hits to 29460 proteins in 1520 species: Archae - 47; Bacteria - 3050; Metazoa - 10477; Fungi - 6558; Plants - 8176; Viruses - 3; Other Eukaryotes - 1237 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      21383812..21385709 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104570.3 → NP_176086.1  cytochrome P450, family 96, subfamily A, polypeptide 15 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176086.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FVS9
      UniProtKB/TrEMBL
      A0A178WN57
      Conserved Domains (1) summary
      PLN02169
      Location:1 → 497
      PLN02169; fatty acid (omega-1)-hydroxylase/midchain alkane hydroxylase

    2. NM_001124037.1 → NP_001117509.1  cytochrome P450, family 96, subfamily A, polypeptide 15 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117509.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WN57, B3H7K7
      Conserved Domains (1) summary
      cl12078
      Location:1 → 424
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FVS9.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.