SKIP chromatin protein family [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: SKIP
Official Full Name: chromatin protein family
Primary source: TAIR:AT1G77180
Locus tag: AT1G77180
See related: Araport:AT1G77180
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: SNW/Ski-interacting protein; T14N5.5; T14N5_5
Summary: Encodes a putative transcriptional factor. Shows transcriptional activator activity in yeast. Involved in response to abscisic acid, salt and osmotic stress.
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Genomic context

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See SKIP in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 2

Sequence:: Chromosome: 1; NC_003070.9 (28999577..29002143, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

SKIP regulates floral transition and environmental fitness via its incorporation into two distinct complexes.
Title: SKIP regulates environmental fitness and floral transition by forming two distinct complexes in Arabidopsis.
SKIP is required for the splicing of serrated leaves and early flowering (SEF) pre-messenger RNA (mRNA), which encodes a component of the ATP-dependent SWR1 chromatin remodeling complex (SWR1-C).
Title: SKIP controls flowering time via the alternative splicing of SEF pre-mRNA in Arabidopsis.
The SNW Domain of SKIP Is Required for Its Integration into the Spliceosome and Its Interaction with the Paf1 Complex in Arabidopsis
Title: The SNW Domain of SKIP Is Required for Its Integration into the Spliceosome and Its Interaction with the Paf1 Complex in Arabidopsis.
Study shows a conserved Interaction between SKIP and SMP1/2 Aids in Recruiting the Second-Step Splicing Factors to the Spliceosome in Arabidopsis.
Title: A Conserved Interaction between SKIP and SMP1/2 Aids in Recruiting the Second-Step Splicing Factors to the Spliceosome in Arabidopsis.
SKIP interacted with the Paf1c to modulate the expression of FLC clade genes at the transcriptional level.
Title: SKIP Interacts with the Paf1 Complex to Regulate Flowering via the Activation of FLC Transcription in Arabidopsis.
SKIP Confers Osmotic Tolerance during Salt Stress by Controlling Alternative Gene Splicing in Arabidopsis
Title: SKIP Confers Osmotic Tolerance during Salt Stress by Controlling Alternative Gene Splicing in Arabidopsis.
Data indicate that AtSKIP participates in cytokinin-regulated promotion of leaf growth in photomorphogenesis, and that phosphorylation interferes with AtSKIP normal function.
Title: AtSKIP functions as a mediator between cytokinin and light signaling pathway in Arabidopsis thaliana.
SKIP is essential for normal function of the circadian clock.
Title: SKIP is a component of the spliceosome linking alternative splicing and the circadian clock in Arabidopsis.
AtSKIP functions as both a positive regulator and putative potential transcription factor in the abiotic stress signalling pathway. [AtSKIP]
Title: A putative novel transcription factor, AtSKIP, is involved in abscisic acid signalling and confers salt and osmotic tolerance in Arabidopsis.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001036214.3

Supported by ESTs:

NM_001198487.1

Supported by ESTs:

NM_106368.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables pre-mRNA binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within RNA splicing	ISS Inferred from Sequence or Structural Similarity more info	PubMed
acts_upstream_of_or_within mRNA splicing, via spliceosome	IPI Inferred from Physical Interaction more info	PubMed
acts_upstream_of_or_within positive regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within regulation of circadian rhythm	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of photoperiodism, flowering	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to abscisic acid	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to mannitol	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to salt stress	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within vegetative to reproductive phase transition of meristem	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	HDA more info	PubMed
located_in nucleolus	HDA more info	PubMed
located_in nucleus	HDA more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: chromatin protein family

NP_001031291.1

SKIP; FUNCTIONS IN: transcription activator activity; INVOLVED IN: response to salt stress, response to mannitol stimulus, RNA splicing, response to abscisic acid stimulus; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: SKI-interacting protein, SKIP (InterPro:IPR017862), SKI-interacting protein SKIP, SNW domain (InterPro:IPR004015); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NP_001185416.1

SKIP; CONTAINS InterPro DOMAIN/s: SKI-interacting protein, SKIP (InterPro:IPR017862), SKI-interacting protein SKIP, SNW domain (InterPro:IPR004015).

NP_565151.1

SKIP; FUNCTIONS IN: transcription activator activity; INVOLVED IN: response to salt stress, response to mannitol stimulus, RNA splicing, response to abscisic acid stimulus; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: SKI-interacting protein, SKIP (InterPro:IPR017862), SKI-interacting protein SKIP, SNW domain (InterPro:IPR004015); Has 9534 Blast hits to 6488 proteins in 453 species: Archae - 14; Bacteria - 426; Metazoa - 4688; Fungi - 1154; Plants - 570; Viruses - 47; Other Eukaryotes - 2635 (source: NCBI BLink).