ZAP1 zinc-dependent activator protein-1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: ZAP1
Official Full Name: zinc-dependent activator protein-1
Primary source: TAIR:AT2G04880
Locus tag: AT2G04880
See related: Araport:AT2G04880
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATWRKY1; F1O13.1; F1O13_1; WRKY1; zinc-dependent activator protein-1
Summary: Encodes WRKY1, a member of the WRKY transcription factors in plants involved in disease resistance, abiotic stress, senescence as well as in some developmental processes. WRKY1 is involved in the salicylic acid signaling pathway. The crystal structure of the WRKY1 C-terminal domain revealed a zinc-binding site and identified the DNA-binding residues of WRKY1.
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Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Arabidopsis WRKY1 promotes monocarpic senescence by integrative regulation of flowering, leaf senescence, and nitrogen remobilization.
Title: Arabidopsis WRKY1 promotes monocarpic senescence by integrative regulation of flowering, leaf senescence, and nitrogen remobilization.
Linker histone variant HIS1-3 and WRKY1 oppositely regulate salt stress tolerance in Arabidopsis.
Title: Linker histone variant HIS1-3 and WRKY1 oppositely regulate salt stress tolerance in Arabidopsis.
AtWRKY1 negatively regulates the response of Arabidopsis thaliana to Pst. DC3000.
Title: AtWRKY1 negatively regulates the response of Arabidopsis thaliana to Pst. DC3000.
Crystal structures of N-terminal WRKY transcription factors and DNA complexes.
Title: Crystal structures of N-terminal WRKY transcription factors and DNA complexes.
The role of WRKY1 in gene expression and stomatal closure under drought stress are reported.
Title: WRKY1 regulates stomatal movement in drought-stressed Arabidopsis thaliana.
A molecular model of WRKY1 protein-DNA complex from site-directed mutagenesis studies.
Title: DNA binding mechanism revealed by high resolution crystal structure of Arabidopsis thaliana WRKY1 protein.
The preliminary X-ray analysis was undertaken. The crystal diffracted to 2.50 A resolution in-house and belongs to space group P2(1)
Title: Crystallization and preliminary X-ray analysis of the C-terminal WRKY domain of Arabidopsis thaliana WRKY1 transcription factor.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_126520.4

NM_179605.3

Function	Evidence Code	Pubs
enables DNA binding	IMP Inferred from Mutant Phenotype more info	PubMed
enables DNA-binding transcription factor activity	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables transcription cis-regulatory region binding	IPI Inferred from Physical Interaction more info	PubMed
enables zinc ion binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within positive regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in response to salicylic acid	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within salicylic acid mediated signaling pathway	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	HDA more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

NP_178565.1

zinc-dependent activator protein-1 (ZAP1); CONTAINS InterPro DOMAIN/s: DNA-binding WRKY (InterPro:IPR003657); BEST Arabidopsis thaliana protein match is: WRKY family transcription factor family protein (TAIR:AT4G26640.2); Has 5944 Blast hits to 3097 proteins in 197 species: Archae - 0; Bacteria - 0; Metazoa - 9; Fungi - 0; Plants - 5898; Viruses - 0; Other Eukaryotes - 37 (source: NCBI BLink).

NP_849936.1

zinc-dependent activator protein-1 (ZAP1); CONTAINS InterPro DOMAIN/s: DNA-binding WRKY (InterPro:IPR003657); BEST Arabidopsis thaliana protein match is: WRKY family transcription factor family protein (TAIR:AT4G26640.2); Has 5746 Blast hits to 3098 proteins in 197 species: Archae - 0; Bacteria - 0; Metazoa - 9; Fungi - 2; Plants - 5699; Viruses - 0; Other Eukaryotes - 36 (source: NCBI BLink).