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    BTB/POZ domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838782, updated on 18-Sep-2024

    Summary

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    Official Full Name
    BTB/POZ domain-containing protein
    Primary source
    TAIR:AT1G21780
    Locus tag
    AT1G21780
    See related
    Araport:AT1G21780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F8K7.22; F8K7_22
    Summary
    BTB/POZ domain-containing protein. Contains similarity to gb:AJ000644 SPOP (speckle-type POZ protein) from Homo sapiens and contains a PF:00651 BTB/POZ domain. ESTs gb:T75841, gb:R89974, gb:R30221, gb:N96386, gb:T76457, gb:AI100013 and gb:T76456 come from this gene;supported by full-length. Interacts with CUL3A and CUL3B.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (7651882..7654014)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene PDI-like 1-1 Neighboring gene F-box protein 7 Neighboring gene Acyl-CoA N-acyltransferases (NAT) superfamily protein Neighboring gene TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein Neighboring gene tRNA-Gln

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cullins 3a and 3b assemble with members of the broad complex/tramtrack/bric-a-brac (BTB) protein family to form essential ubiquitin-protein ligases (E3s) in Arabidopsis. Gingerich DJ, et al. J Biol Chem, 2005 May 13. PMID 15749712
    2. Molecular and functional characterization of Arabidopsis Cullin 3A. Dieterle M, et al. Plant J, 2005 Feb. PMID 15659098
    3. Arabidopsis has two redundant Cullin3 proteins that are essential for embryo development and that interact with RBX1 and BTB proteins to form multisubunit E3 ubiquitin ligase complexes in vivo. Figueroa P, et al. Plant Cell, 2005 Apr. PMID 15772280, Free PMC Article
    4. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001084105.1
    NM_102027.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul3-RING ubiquitin ligase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    BTB/POZ domain-containing protein
    NP_001077574.1
    • BTB/POZ domain-containing protein; CONTAINS InterPro DOMAIN/s: BTB/POZ (InterPro:IPR013069), BTB/POZ fold (InterPro:IPR011333), Kelch related (InterPro:IPR013089), BTB/POZ-like (InterPro:IPR000210); BEST Arabidopsis thaliana protein match is: BTB/POZ domain-containing protein (TAIR:AT1G55760.1); Has 5195 Blast hits to 5164 proteins in 157 species: Archae - 0; Bacteria - 0; Metazoa - 3886; Fungi - 25; Plants - 983; Viruses - 68; Other Eukaryotes - 233 (source: NCBI BLink).
    NP_173597.1
    • BTB/POZ domain-containing protein; CONTAINS InterPro DOMAIN/s: BTB/POZ (InterPro:IPR013069), BTB/POZ fold (InterPro:IPR011333), Kelch related (InterPro:IPR013089), BTB/POZ-like (InterPro:IPR000210); BEST Arabidopsis thaliana protein match is: BTB/POZ domain-containing protein (TAIR:AT1G55760.1); Has 5195 Blast hits to 5164 proteins in 157 species: Archae - 0; Bacteria - 0; Metazoa - 3886; Fungi - 25; Plants - 983; Viruses - 68; Other Eukaryotes - 233 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7651882..7654014
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001084105.1 → NP_001077574.1  BTB/POZ domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077574.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WS66, Q9XHZ8
      UniProtKB/TrEMBL
      A0A178W1G9, A0A5S9VFP9
      Conserved Domains (1) summary
      pfam00651
      Location:151 → 255
      BTB; BTB/POZ domain

    2. NM_102027.3 → NP_173597.1  BTB/POZ domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173597.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WS66, Q9XHZ8
      UniProtKB/TrEMBL
      A0A178W1G9, A0A5S9VFP9
      Conserved Domains (1) summary
      pfam00651
      Location:151 → 255
      BTB; BTB/POZ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XHZ8.1

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