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    ATL2 TOXICOS EN LEVADURA 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820924, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATL2
    Official Full Name
    TOXICOS EN LEVADURA 2
    Primary source
    TAIR:AT3G16720
    Locus tag
    AT3G16720
    See related
    Araport:AT3G16720
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    TL2; TOXICOS EN LEVADURA 2
    Summary
    RING-H2 protein induced after exposure to chitin or inactivated crude cellulase preparations.
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    Genomic context

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    See ATL2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_003074.8 (5692607..5694181)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene uncharacterized protein Neighboring gene condensin-2 complex subunit H2-like protein Neighboring gene F-box and associated interaction domains-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Cuticle Mutant eca2 Modifies Plant Defense Responses to Biotrophic and Necrotrophic Pathogens and Herbivory Insects. Blanc C, et al. Mol Plant Microbe Interact, 2018 Mar. PMID 29130376
    2. The ATL gene family from Arabidopsis thaliana and Oryza sativa comprises a large number of putative ubiquitin ligases of the RING-H2 type. Serrano M, et al. J Mol Evol, 2006 Apr. PMID 16557337
    3. Isolation and gene expression analysis of Arabidopsis thaliana mutants with constitutive expression of ATL2, an early elicitor-response RING-H2 zinc-finger gene. Serrano M, et al. Genetics, 2004 Jun. PMID 15238540, Free PMC Article
    4. Early elicitor induction in members of a novel multigene family coding for highly related RING-H2 proteins in Arabidopsis thaliana. Salinas-Mondragón RE, et al. Plant Mol Biol, 1999 Jul. PMID 10480382
    5. Genetic interactions of a putative Arabidopsis thaliana ubiquitin-ligase with components of the Saccharomyces cerevisiae ubiquitination machinery. Aguilar-Henonin L, et al. Curr Genet, 2006 Oct. PMID 16897085

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ECA2-dependent responses are involved in the nonhost defense mechanism against biotrophic and necrotrophic pathogens and against a generalist insect by modulation and priming of innate immunity and late defense responses.[Eca2]
      Title: The Cuticle Mutant eca2 Modifies Plant Defense Responses to Biotrophic and Necrotrophic Pathogens and Herbivory Insects.
    2. The ATL protein comprising Ubiquitin Ligases that is one of a multigene family.
      Title: The ATL gene family from Arabidopsis thaliana and Oryza sativa comprises a large number of putative ubiquitin ligases of the RING-H2 type.
    3. ATL2 and other members of the ATL family are activated linking to the induction of this putative class of ubiquitin ligases to plant defense signaling pathways. [ATL2]
      Title: Isolation and gene expression analysis of Arabidopsis thaliana mutants with constitutive expression of ATL2, an early elicitor-response RING-H2 zinc-finger gene.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_112545.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    TOXICOS EN LEVADURA 2
    NP_188294.1
    • TOXICOS EN LEVADURA 2 (ATL2); FUNCTIONS IN: zinc ion binding; INVOLVED IN: response to chitin, defense response; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT4G15975.1); Has 9711 Blast hits to 9689 proteins in 300 species: Archae - 0; Bacteria - 2; Metazoa - 2552; Fungi - 813; Plants - 5050; Viruses - 85; Other Eukaryotes - 1209 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5692607..5694181
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112545.2 → NP_188294.1  TOXICOS EN LEVADURA 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188294.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O24008, Q4FE42, Q8L9T5, Q9LUR1
      UniProtKB/TrEMBL
      A0A5S9XCZ8, A0A654FD72
      Conserved Domains (2) summary
      TIGR00599
      Location:119 → 284
      rad18; DNA repair protein rad18
      cd16461
      Location:118 → 161
      RING-H2_EL5_like; RING finger, H2 subclass, found in rice E3 ubiquitin-protein ligase EL5 and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L9T5.2

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