U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FHY3 far-red elongated hypocotyls 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821781, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FHY3
    Official Full Name
    far-red elongated hypocotyls 3
    Primary source
    TAIR:AT3G22170
    Locus tag
    AT3G22170
    See related
    Araport:AT3G22170
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CHLOROPLAST DIVISION MUTANT 45; CPD45; far-red elongated hypocotyls 3
    Summary
    A component of the PHYA signaling network, mediates the FR-HIR response to far-red light in concert with FAR1.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FHY3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (7821997..7826196, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene VQ motif-containing protein Neighboring gene ncRNA Neighboring gene DHHC-type zinc finger family protein Neighboring gene uncharacterized protein Neighboring gene IQ-domain 5

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Arabidopsis FHY3 specifically gates phytochrome signaling to the circadian clock. Allen T, et al. Plant Cell, 2006 Oct. PMID 17012604, Free PMC Article
    2. FAR-RED ELONGATED HYPOCOTYLS3 negatively regulates shade avoidance responses in Arabidopsis. Ma L, et al. Plant Cell Environ, 2019 Dec. PMID 31351015
    3. Genome-wide binding site analysis of FAR-RED ELONGATED HYPOCOTYL3 reveals its novel function in Arabidopsis development. Ouyang X, et al. Plant Cell, 2011 Jul. PMID 21803941, Free PMC Article
    4. Arabidopsis FAR-RED ELONGATED HYPOCOTYL3 negatively regulates carbon starvation responses. Ma L, et al. Plant Cell Environ, 2021 Jun. PMID 33715163
    5. Arabidopsis FHY3 defines a key phytochrome A signaling component directly interacting with its homologous partner FAR1. Wang H, et al. EMBO J, 2002 Mar 15. PMID 11889039, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FHY3 interacts with phytochrome B and regulates seed dormancy and germination.
      Title: FHY3 interacts with phytochrome B and regulates seed dormancy and germination.
    2. Arabidopsis FAR-RED ELONGATED HYPOCOTYL3 negatively regulates carbon starvation responses.
      Title: Arabidopsis FAR-RED ELONGATED HYPOCOTYL3 negatively regulates carbon starvation responses.
    3. Arabidopsis FAR-RED ELONGATED HYPOCOTYL3 Integrates Age and Light Signals to Negatively Regulate Leaf Senescence.
      Title: Arabidopsis FAR-RED ELONGATED HYPOCOTYL3 Integrates Age and Light Signals to Negatively Regulate Leaf Senescence.
    4. Transcription Factors FHY3 and FAR1 Regulate Light-Induced CIRCADIAN CLOCK ASSOCIATED1 Gene Expression in Arabidopsis.
      Title: Transcription Factors FHY3 and FAR1 Regulate Light-Induced CIRCADIAN CLOCK ASSOCIATED1 Gene Expression in Arabidopsis.
    5. FHY3 and FAR1 Integrate Light Signals with the miR156-SPL Module-Mediated Aging Pathway to Regulate Arabidopsis Flowering.
      Title: FHY3 and FAR1 Integrate Light Signals with the miR156-SPL Module-Mediated Aging Pathway to Regulate Arabidopsis Flowering.
    6. the light-signalling protein FHY3 positively regulates the transcription of PAR1 and PAR2, which encode two key negative regulators of shade avoidance responses, thus repressing plant responses to shade signals.
      Title: FAR-RED ELONGATED HYPOCOTYLS3 negatively regulates shade avoidance responses in Arabidopsis.
    7. Arabidopsis FHY3 and FAR1 Regulate the Balance between Growth and Defense Responses under Shade Conditions.
      Title: Arabidopsis FHY3 and FAR1 Regulate the Balance between Growth and Defense Responses under Shade Conditions.
    8. the light-signaling proteins FHY3 and FAR1 influence starch synthesis and starch granule formation through transcriptional activation of ISA2.
      Title: Arabidopsis thaliana FAR-RED ELONGATED HYPOCOTYLS3 (FHY3) and FAR-RED-IMPAIRED RESPONSE1 (FAR1) modulate starch synthesis in response to light and sugar.
    9. In shoot apical meristem, FHY3 directly represses CLV3, which consequently regulates WUS to maintain the stem cell pool.
      Title: FAR-RED ELONGATED HYPOCOTYL3 activates SEPALLATA2 but inhibits CLAVATA3 to regulate meristem determinacy and maintenance in Arabidopsis.
    10. FHY3 and FAR1 directly bind the promoter of MIPS1 to activate its expression and thereby promote inositol biosynthesis to prevent
      Title: Arabidopsis FHY3 and FAR1 Regulate Light-Induced myo-Inositol Biosynthesis and Oxidative Stress Responses by Transcriptional Activation of MIPS1.
    Submit: New GeneRIF Correction See all GeneRIFs (22)

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001125201.2
    NM_113114.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within circadian rhythm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of circadian rhythm IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of circadian rhythm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within red or far-red light signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within red, far-red light phototransduction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to far red light IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    far-red elongated hypocotyls 3
    NP_001118673.1
    • far-red elongated hypocotyls 3 (FHY3); CONTAINS InterPro DOMAIN/s: MULE transposase, conserved domain (InterPro:IPR018289), Transcription factor, FAR1-related (InterPro:IPR004330), Zinc finger, PMZ-type (InterPro:IPR006564), Zinc finger, SWIM-type (InterPro:IPR007527), Glycoside hydrolase, family 10 (InterPro:IPR001000); BEST Arabidopsis thaliana protein match is: FRS (FAR1 Related Sequences) transcription factor family (TAIR:AT4G15090.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_188856.2
    • far-red elongated hypocotyls 3 (FHY3); CONTAINS InterPro DOMAIN/s: MULE transposase, conserved domain (InterPro:IPR018289), Transcription factor, FAR1-related (InterPro:IPR004330), Zinc finger, PMZ-type (InterPro:IPR006564), Zinc finger, SWIM-type (InterPro:IPR007527), Glycoside hydrolase, family 10 (InterPro:IPR001000); BEST Arabidopsis thaliana protein match is: FRS (FAR1 Related Sequences) transcription factor family (TAIR:AT4G15090.1); Has 1557 Blast hits to 1407 proteins in 50 species: Archae - 0; Bacteria - 0; Metazoa - 7; Fungi - 102; Plants - 1437; Viruses - 0; Other Eukaryotes - 11 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      7821997..7826196 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001125201.2 → NP_001118673.1  far-red elongated hypocotyls 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001118673.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LIE5
      UniProtKB/TrEMBL
      A0A178VJL5, A0A5S9XEP5
      Conserved Domains (1) summary
      PLN03097
      Location:1 → 839
      FHY3; Protein FAR-RED ELONGATED HYPOCOTYL 3; Provisional

    2. NM_113114.3 → NP_188856.2  far-red elongated hypocotyls 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188856.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LIE5
      UniProtKB/TrEMBL
      A0A178VJL5, A0A5S9XEP5
      Conserved Domains (1) summary
      PLN03097
      Location:1 → 839
      FHY3; Protein FAR-RED ELONGATED HYPOCOTYL 3; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LIE5.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools