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    GAE5 UDP-D-glucuronate 4-epimerase 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826833, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GAE5
    Official Full Name
    UDP-D-glucuronate 4-epimerase 5
    Primary source
    TAIR:AT4G12250
    Locus tag
    AT4G12250
    See related
    Araport:AT4G12250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T4C9.90; T4C9_90; UDP-D-glucuronate 4-epimerase 5
    Summary
    UDP-D-glucuronate 4-epimerase
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    Genomic context

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    See GAE5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    1
    Sequence:
    Chromosome: 4; NC_003075.7 (7289192..7291120, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene zinc finger (C2H2 type) family protein Neighboring gene pseudo Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The biosynthesis of D-Galacturonate in plants. functional cloning and characterization of a membrane-anchored UDP-D-Glucuronate 4-epimerase from Arabidopsis. Mølhøj M, et al. Plant Physiol, 2004 Jul. PMID 15247385, Free PMC Article
    2. Separating Golgi Proteins from Cis to Trans Reveals Underlying Properties of Cisternal Localization. Parsons HT, et al. Plant Cell, 2019 Sep. PMID 31266899, Free PMC Article
    3. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    4. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_117295.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables UDP-glucuronate 4-epimerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-glucuronate 4-epimerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi medial cisterna HDA PubMed 
    located_in endosome HDA PubMed 
    located_in trans-Golgi network HDA PubMed 

    General protein information

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    Preferred Names
    UDP-D-glucuronate 4-epimerase 5
    NP_192962.1
    • UDP-D-glucuronate 4-epimerase 5 (GAE5); FUNCTIONS IN: UDP-glucuronate 4-epimerase activity, catalytic activity; INVOLVED IN: cellular metabolic process, carbohydrate metabolic process, nucleotide-sugar metabolic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040), Nucleotide sugar epimerase (InterPro:IPR008089); BEST Arabidopsis thaliana protein match is: UDP-D-glucuronate 4-epimerase 3 (TAIR:AT4G00110.1); Has 40243 Blast hits to 40231 proteins in 2957 species: Archae - 760; Bacteria - 24181; Metazoa - 696; Fungi - 354; Plants - 1138; Viruses - 37; Other Eukaryotes - 13077 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      7289192..7291120 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117295.4 → NP_192962.1  UDP-D-glucuronate 4-epimerase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192962.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q949N3, Q9STI6
      UniProtKB/TrEMBL
      A0A178UUD1, A0A5S9XS82, A0A654FNM5, A0A7G2F294
      Conserved Domains (1) summary
      cl21454
      Location:97 → 423
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9STI6.1

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