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    TTN8 Structural maintenance of chromosomes (SMC) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824632, updated on 18-Sep-2024

    Summary

    Official Symbol
    TTN8
    Official Full Name
    Structural maintenance of chromosomes (SMC) family protein
    Primary source
    TAIR:AT3G54670
    Locus tag
    AT3G54670
    See related
    Araport:AT3G54670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSMC1; SMC1; STRUCTURAL MAINTENANCE OF CHROMOSOMES 1; TITAN8
    Summary
    Encodes a member of the Arabidopsis cohesin complex that is essential for viability and sister chromatid alignment.
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    Genomic context

    See TTN8 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    18
    Sequence:
    Chromosome: 3; NC_003074.8 (20235506..20244046)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene RNI-like superfamily protein Neighboring gene glutathione reductase Neighboring gene proteophosphoglycan-like protein Neighboring gene Sugar isomerase (SIS) family protein

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_001339686.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in chromosome segregation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of cohesin complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    Structural maintenance of chromosomes (SMC) family protein
    NP_001319748.1
    • TITAN8 (TTN8); FUNCTIONS IN: transporter activity, ATP binding; INVOLVED IN: sister chromatid cohesion, chromosome segregation; LOCATED IN: cohesin complex, nucleus, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: SMCs flexible hinge (InterPro:IPR010935), RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: structural maintenance of chromosome 3 (TAIR:AT5G48600.1); Has 200429 Blast hits to 91047 proteins in 3650 species: Archae - 2506; Bacteria - 36447; Metazoa - 81443; Fungi - 15311; Plants - 9097; Viruses - 946; Other Eukaryotes - 54679 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20235506..20244046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001339686.1NP_001319748.1  Structural maintenance of chromosomes (SMC) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JE01, F4JE02, Q0WSY5, Q6Q1P4, Q9M1T3
      UniProtKB/TrEMBL
      A0A5S9XKT5, A0A654FHX4