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    ASG2 transducin family protein / WD-40 repeat family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830961, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ASG2
    Official Full Name
    transducin family protein / WD-40 repeat family protein
    Primary source
    TAIR:AT5G10940
    Locus tag
    AT5G10940
    See related
    Araport:AT5G10940
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ALTERED SEED GERMINATION 2; T30N20.210; T30N20_210
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    Genomic context

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    See ASG2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    19
    Sequence:
    Chromosome: 5; NC_003076.8 (3448535..3454286, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene L-Aspartase-like family protein Neighboring gene CBL-interacting protein kinase 5 Neighboring gene uncharacterized protein Neighboring gene microRNA ath-MIR156d precursor Neighboring gene Tudor/PWWP/MBT superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Remarkable Evolutionary Conservation of Antiobesity ADIPOSE/WDTC1 Homologs in Animals and Plants. Ducos E, et al. Genetics, 2017 Sep. PMID 28663238, Free PMC Article
    2. ASG2 is a farnesylated DWD protein that acts as ABA negative regulator in Arabidopsis. Dutilleul C, et al. Plant Cell Environ, 2016 Jan. PMID 26147561
    3. Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases. Lee JH, et al. Plant Cell, 2008 Jan. PMID 18223036, Free PMC Article
    4. Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes. Zhang Y, et al. Plant Cell, 2008 Jun. PMID 18552200, Free PMC Article
    5. Toward an interaction map of the two-component signaling pathway of Arabidopsis thaliana. Dortay H, et al. J Proteome Res, 2008 Sep. PMID 18642946

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203357.2
    NM_121132.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of fatty acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    transducin family protein / WD-40 repeat family protein
    NP_001190286.1
    • transducin family protein / WD-40 repeat family protein; FUNCTIONS IN: nucleotide binding; INVOLVED IN: biological_process unknown; LOCATED IN: CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT3G45620.1).
    NP_568242.1
    • transducin family protein / WD-40 repeat family protein; FUNCTIONS IN: nucleotide binding; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT3G45620.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3448535..3454286 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001203357.2 → NP_001190286.1  transducin family protein / WD-40 repeat family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190286.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UF65, A0A654G076
      Conserved Domains (3) summary
      sd00006
      Location:402 → 433
      TPR; TPR repeat [structural motif]
      sd00039
      Location:55 → 91
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:41 → 247
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_121132.4 → NP_568242.1  transducin family protein / WD-40 repeat family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568242.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94BQ3, Q9LEU6
      UniProtKB/TrEMBL
      A0A178UF48, A0A5S9Y353
      Conserved Domains (3) summary
      sd00006
      Location:405 → 436
      TPR; TPR repeat [structural motif]
      sd00039
      Location:54 → 89
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:41 → 247
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94BQ3.1

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