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    FASS tonneau 2 (TON2) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831976, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FASS
    Official Full Name
    tonneau 2 (TON2)
    Primary source
    TAIR:AT5G18580
    Locus tag
    AT5G18580
    See related
    Araport:AT5G18580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EMB40; EMBRYO DEFECTIVE 40; FASS 1; FASS 2; FS1; GDO; GORDO; T28N17.60; T28N17_60; TON2; TONNEAU 2
    Summary
    fass mutants have aberrant cell shapes due to defects in arrangement of cortical microtubules. Encodes a protein highly conserved in higher plants and similar in its C-terminal part to B' regulatory subunits of type 2A protein phosphatases. Interacts with an Arabidopsis type A subunit of PP2A in the yeast two-hybrid system.
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    Genomic context

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    See FASS in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    12
    Sequence:
    Chromosome: 5; NC_003076.8 (6174972..6178401)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene GTP1/OBG family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene Thioredoxin superfamily protein Neighboring gene Protein kinase superfamily protein Neighboring gene chromatin remodeling factor17

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TONNEAU2/FASS regulates the geometry of microtubule nucleation and cortical array organization in interphase Arabidopsis cells. Kirik A, et al. Plant Cell, 2012 Mar. PMID 22395485, Free PMC Article
    2. Organization of cortical microtubules at the plasma membrane in Arabidopsis. McClinton RS, et al. Planta, 1997. PMID 9129335
    3. AtOFPs regulate cell elongation by modulating microtubule orientation via direct interaction with TONNEAU2. Zhang X, et al. Plant Sci, 2020 Mar. PMID 32005401
    4. The Arabidopsis TONNEAU2 gene encodes a putative novel protein phosphatase 2A regulatory subunit essential for the control of the cortical cytoskeleton. Camilleri C, et al. Plant Cell, 2002 Apr. PMID 11971138, Free PMC Article
    5. SIS8, a putative mitogen-activated protein kinase kinase kinase, regulates sugar-resistant seedling development in Arabidopsis. Huang Y, et al. Plant J, 2014 Feb. PMID 24320620

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtOFPs regulate cell elongation by modulating microtubule orientation via direct interaction with TONNEAU2.
      Title: AtOFPs regulate cell elongation by modulating microtubule orientation via direct interaction with TONNEAU2.
    2. Microtubule branching nucleation is specifically promoted by the B'' regulatory subunit of FASS.
      Title: TONNEAU2/FASS regulates the geometry of microtubule nucleation and cortical array organization in interphase Arabidopsis cells.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_121863.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein phosphatase regulator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cortical cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in preprophase band assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within unidimensional cell growth TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in phragmoplast HDA PubMed 
    located_in spindle HDA PubMed 

    General protein information

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    Preferred Names
    tonneau 2 (TON2)
    NP_568364.1
    • FASS 1 (FASS); CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992); BEST Arabidopsis thaliana protein match is: Calcium-binding EF-hand family protein (TAIR:AT5G28850.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      6174972..6178401
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121863.4 → NP_568364.1  tonneau 2 (TON2) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568364.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FEE2
      UniProtKB/TrEMBL
      A0A178UAP1, A0A7G2F8I4
      Conserved Domains (1) summary
      cd21505
      Location:72 → 465
      PPP2R3C; serine/threonine protein phosphatase 2A regulatory subunit B" subunit gamma
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FEE2.1

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