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    SSP4 SCP1-like small phosphatase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834684, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SSP4
    Official Full Name
    SCP1-like small phosphatase 4
    Primary source
    TAIR:AT5G46410
    Locus tag
    AT5G46410
    See related
    Araport:AT5G46410
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MPL12.21; MPL12_21; SCP1-like small phosphatase 4
    Summary
    Encodes a SCP1-like small phosphatase (SSP). Three SSPs form a unique group with long N-terminal extensions: AT5G46410 (SSP4), AT5G11860 (SSP5), AT4G18140 (SSP4b). SSP4 and SSP4b were localized exclusively in the nuclei, whereas SSP5 accumulated in both nuclei and cytoplasm. All three SSPs encodes active CTD phosphatases like animal SCP1 family proteins, with distinct substrate specificities: SSP4 and SSP4b could dephosphorylate both Ser2-PO(4) and Ser5-PO(4) of CTD, whereas SSP5 dephosphorylated only Ser5-PO(4).
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    Genomic context

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    See SSP4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (18825100..18829624)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene 16S rRNA processing protein RimM family Neighboring gene Ribosomal protein L32e Neighboring gene ncRNA Neighboring gene PPR containing-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis SCP1-like small phosphatases differentially dephosphorylate RNA polymerase II C-terminal domain. Feng Y, et al. Biochem Biophys Res Commun, 2010 Jun 25. PMID 20513350
    2. An abscisic acid-responsive protein interaction network for sucrose non-fermenting related kinase1 in abiotic stress response. Carianopol CS, et al. Commun Biol, 2020 Mar 26. PMID 32218501, Free PMC Article
    3. A mesoscale abscisic acid hormone interactome reveals a dynamic signaling landscape in Arabidopsis. Lumba S, et al. Dev Cell, 2014 May 12. PMID 24823379
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001125911.1
    NM_001344678.1
    NM_124011.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA polymerase II CTD heptapeptide repeat phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SCP1-like small phosphatase 4
    NP_001119383.1
    • SCP1-like small phosphatase 4 (SSP4); CONTAINS InterPro DOMAIN/s: Dullard-like phosphatase domain (InterPro:IPR011948), NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: SCP1-like small phosphatase 4b (TAIR:AT4G18140.3); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_199453.2
    • SCP1-like small phosphatase 4 (SSP4); CONTAINS InterPro DOMAIN/s: Dullard-like phosphatase domain (InterPro:IPR011948), NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: SCP1-like small phosphatase 4b (TAIR:AT4G18140.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      18825100..18829624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124011.4 → NP_199453.2  SCP1-like small phosphatase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199453.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UF00, A0A384KWT4, A0A5S9YDV9, Q8GYV2, Q8VY28
      Conserved Domains (1) summary
      TIGR02251
      Location:281 → 440
      HIF-SF_euk; Dullard-like phosphatase domain

    2. NM_001344678.1 → NP_001332006.1  SCP1-like small phosphatase 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UF00, A0A384KWT4, A0A5S9YDV9, Q8GYV2, Q8VY28
      Conserved Domains (1) summary
      TIGR02251
      Location:281 → 440
      HIF-SF_euk; Dullard-like phosphatase domain

    3. NM_001125911.1 → NP_001119383.1  SCP1-like small phosphatase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119383.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9YDV9, F4KHG9, Q8GYV2
      Conserved Domains (1) summary
      TIGR02251
      Location:284 → 443
      HIF-SF_euk; Dullard-like phosphatase domain
    Nucleotide Protein
    Heading Accession and Version

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