CRL crumpled leaf [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: CRL
Official Full Name: crumpled leaf
Primary source: TAIR:AT5G51020
Locus tag: AT5G51020
See related: Araport:AT5G51020
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: CAA33; constitutive activator of AAA-ATPase; CRUMPLED LEAF; K3K7.20; K3K7_20
Summary: Encodes CRL (CRUMPLED LEAF), a protein localized in the outer envelope membrane of plastids. Mutation in this gene affects the pattern of cell division, cell differentiation and plastid division.
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See CRL in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 9

Sequence:: Chromosome: 5; NC_003076.8 (20745349..20747305, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CRUMPLED LEAF supports plastid OUTER ENVELOPE PROTEIN OF 80 KDA complex formation in Arabidopsis.
Title: CRUMPLED LEAF supports plastid OUTER ENVELOPE PROTEIN OF 80 KDA complex formation in Arabidopsis.
The Arabidopsis CRUMPLED LEAF protein, a homolog of the cyanobacterial bilin lyase, retains the bilin-binding pocket for a yet unknown function.
Title: The Arabidopsis CRUMPLED LEAF protein, a homolog of the cyanobacterial bilin lyase, retains the bilin-binding pocket for a yet unknown function.
In the crl mutant, cell cycle regulation is altered drastically and meristematic cells prematurely enter differentiation, leading to reduced plant stature and early endoreduplication in the leaves.
Title: Chloroplast dysfunction causes multiple defects in cell cycle progression in the Arabidopsis crumpled leaf mutant.
The stomatal opening of guard cells with (crl-ch) or without chloroplasts (crl-no ch) in one epidermis of crl (crumpled leaf) mutant in Arabidopsis, were compared.
Title: Lacking chloroplasts in guard cells of crumpled leaf attenuates stomatal opening: both guard cell chloroplasts and mesophyll contribute to guard cell ATP levels.
Constitutive AAA-ATPase expression, stunted growth, reduced Chl content, disturbed chloroplast division and spontaneous cell deaths in caa33 are caused by the mutation of a single gene, CRL.
Title: The chloroplast division mutant caa33 of Arabidopsis thaliana reveals the crucial impact of chloroplast homeostasis on stress acclimation and retrograde plastid-to-nucleus signaling.
CRL over-expressing plants showed an increased susceptibility to CaLCuV infection (as compared to wt plants) whereas CRL-silenced plants, on the contrary, presented a reduced susceptibility to Cabbage leaf curl virus infection.
Title: The infective cycle of Cabbage leaf curl virus (CaLCuV) is affected by CRUMPLED LEAF (CRL) gene in Arabidopsis thaliana.
crl mutant contains cells lacking detectable plastids; this situation probably results from an unequal partitioning of plastids to each daughter cell. [CRL]
Title: Plant cells without detectable plastids are generated in the crumpled leaf mutant of Arabidopsis thaliana.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

NM_124481.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in cellular response to virus	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within chloroplast fission	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within plastid fission	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of cell division	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to reactive oxygen species	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transport of virus in host, tissue to tissue	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast outer membrane	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
located_in plastid	HDA more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: crumpled leaf

NP_199915.1

CRUMPLED LEAF (CRL); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1001 (InterPro:IPR010404); Has 109 Blast hits to 109 proteins in 37 species: Archae - 0; Bacteria - 64; Metazoa - 0; Fungi - 0; Plants - 31; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink).