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    NRPB7 DNA-directed RNA polymerase II [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836036, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NRPB7
    Official Full Name
    DNA-directed RNA polymerase II
    Primary source
    TAIR:AT5G59180
    Locus tag
    AT5G59180
    See related
    Araport:AT5G59180
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MNC17.16; MNC17_16
    Summary
    Non-catalytic subunit specific to DNA-directed RNA polymerase II; the ortholog of budding yeast RPB7
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    Genomic context

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    See NRPB7 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (23883356..23885305)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene type one serine/threonine protein phosphatase 2 Neighboring gene Proline-rich extensin-like family protein Neighboring gene subtilase family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Native elongation transcript sequencing reveals temperature dependent dynamics of nascent RNAPII transcription in Arabidopsis. Kindgren P, et al. Nucleic Acids Res, 2020 Mar 18. PMID 31863587, Free PMC Article
    2. Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II. Ream TS, et al. Mol Cell, 2009 Jan 30. PMID 19110459, Free PMC Article
    3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The results suggest a role for promoter-proximal RNAPII stalling in predisposing genes for transcriptional activation during plant-environment interactions.
      Title: Native elongation transcript sequencing reveals temperature dependent dynamics of nascent RNAPII transcription in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125308.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase II, core complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase II
    NP_200726.1
    • NRPB7; FUNCTIONS IN: DNA-directed RNA polymerase activity, RNA binding; INVOLVED IN: transcription; LOCATED IN: DNA-directed RNA polymerase II, core complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), Ribosomal protein S1, RNA-binding domain (InterPro:IPR003029), RNA polymerase Rpb7, N-terminal (InterPro:IPR005576); BEST Arabidopsis thaliana protein match is: RNA polymerase Rpb7-like, N-terminal domain (TAIR:AT4G14660.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      23883356..23885305
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125308.4 → NP_200726.1  DNA-directed RNA polymerase II [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200726.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P38421, Q541V8
      UniProtKB/TrEMBL
      A0A178UBZ0, A0A5S9YFK3, A0A7G2FHB4
      Conserved Domains (1) summary
      PTZ00162
      Location:1 → 172
      PTZ00162; DNA-directed RNA polymerase II subunit 7; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38421.1

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