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    Ifitm10 interferon induced transmembrane protein 10 [ Mus musculus (house mouse) ]

    Gene ID: 320802, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ifitm10provided by MGI
    Official Full Name
    interferon induced transmembrane protein 10provided by MGI
    Primary source
    MGI:MGI:2444776
    See related
    Ensembl:ENSMUSG00000045777 AllianceGenome:MGI:2444776
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DSPA3; 6330512M04Rik
    Summary
    Predicted to be active in plasma membrane. Orthologous to human IFITM10 (interferon induced transmembrane protein 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 9.8), lung adult (RPKM 4.5) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ifitm10 in Genome Data Viewer
    Location:
    7 F5; 7 87.9 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (141879572..141927526, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (142325835..142373779, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene keratin associated protein 5-4 Neighboring gene predicted gene 5054 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:149508605-149508858 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:149509431-149509643 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:149539783-149540069 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:149567080-149567427 Neighboring gene STARR-seq mESC enhancer starr_20506 Neighboring gene cathepsin D Neighboring gene predicted gene, 26143

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The dispanins: a novel gene family of ancient origin that contains 14 human members. Sällman Almén M, et al. PLoS One, 2012. PMID 22363774, Free PMC Article
    2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    interferon-induced transmembrane protein 10
    Names
    CD225 family protein FLJ76511 homolog
    dispanin subfamily A member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347541.4 → NP_001334470.2  interferon-induced transmembrane protein 10 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC034099
      Consensus CDS
      CCDS85468.1
      Related
      ENSMUSP00000101608.2, ENSMUST00000105988.2

    2. NM_001347542.2 → NP_001334471.1  interferon-induced transmembrane protein 10 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC034099
      Consensus CDS
      CCDS85467.1
      UniProtKB/Swiss-Prot
      Q8BR26
      Related
      ENSMUSP00000081450.6, ENSMUST00000084412.6
      Conserved Domains (1) summary
      pfam04505
      Location:53 → 119
      CD225; Interferon-induced transmembrane protein

    3. NM_001419315.1 → NP_001406244.1  interferon-induced transmembrane protein 10 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC034099

    4. NM_001419316.1 → NP_001406245.1  interferon-induced transmembrane protein 10 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC034099

    5. NM_001419317.1 → NP_001406246.1  interferon-induced transmembrane protein 10 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC034099

    6. NM_001419318.1 → NP_001406247.1  interferon-induced transmembrane protein 10 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC034099

    7. NM_177265.5 → NP_796239.1  interferon-induced transmembrane protein 10 isoform 2

      See identical proteins and their annotated locations for NP_796239.1

      Status: VALIDATED

      Source sequence(s)
      AC034099
      Consensus CDS
      CCDS40191.1
      UniProtKB/Swiss-Prot
      Q8BR26
      Related
      ENSMUSP00000062728.9, ENSMUST00000059223.15
      Conserved Domains (1) summary
      pfam04505
      Location:53 → 81
      CD225; Interferon-induced transmembrane protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      141879572..141927526 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153170.1 → XP_036009063.1  interferon-induced transmembrane protein 10 isoform X3

      Conserved Domains (1) summary
      pfam04505
      Location:53 → 81
      CD225; Interferon-induced transmembrane protein

    2. XM_011242002.3 → XP_011240304.1  interferon-induced transmembrane protein 10 isoform X1

      Conserved Domains (1) summary
      pfam04505
      Location:124 → 152
      CD225; Interferon-induced transmembrane protein

    3. XM_011242008.4 → XP_011240310.1  interferon-induced transmembrane protein 10 isoform X3

      See identical proteins and their annotated locations for XP_011240310.1

      UniProtKB/Swiss-Prot
      Q8BR26
      Conserved Domains (1) summary
      pfam04505
      Location:53 → 81
      CD225; Interferon-induced transmembrane protein

    4. XM_011242010.3 → XP_011240312.1  interferon-induced transmembrane protein 10 isoform X3

      See identical proteins and their annotated locations for XP_011240312.1

      UniProtKB/Swiss-Prot
      Q8BR26
      Conserved Domains (1) summary
      pfam04505
      Location:53 → 81
      CD225; Interferon-induced transmembrane protein

    5. XM_011242011.4 → XP_011240313.1  interferon-induced transmembrane protein 10 isoform X3

      See identical proteins and their annotated locations for XP_011240313.1

      UniProtKB/Swiss-Prot
      Q8BR26
      Conserved Domains (1) summary
      pfam04505
      Location:53 → 81
      CD225; Interferon-induced transmembrane protein

    6. XM_036153169.1 → XP_036009062.1  interferon-induced transmembrane protein 10 isoform X3

      Conserved Domains (1) summary
      pfam04505
      Location:53 → 81
      CD225; Interferon-induced transmembrane protein

    7. XM_011242012.1 → XP_011240314.1  interferon-induced transmembrane protein 10 isoform X3

      See identical proteins and their annotated locations for XP_011240314.1

      UniProtKB/Swiss-Prot
      Q8BR26
      Conserved Domains (1) summary
      pfam04505
      Location:53 → 81
      CD225; Interferon-induced transmembrane protein

    8. XM_011242006.4 → XP_011240308.1  interferon-induced transmembrane protein 10 isoform X2

      Conserved Domains (1) summary
      pfam04505
      Location:124 → 152
      CD225; Interferon-induced transmembrane protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BR26.3 GenPept UniProtKB/Swiss-Prot:Q8BR26

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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