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    Tomm6 translocase of outer mitochondrial membrane 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 681123, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tomm6provided by RGD
    Official Full Name
    translocase of outer mitochondrial membrane 6provided by RGD
    Primary source
    RGD:1583567
    See related
    AllianceGenome:RGD:1583567
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Prickle4
    Summary
    Predicted to be active in mitochondrion. Orthologous to human TOMM6 (translocase of outer mitochondrial membrane 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 407.1), Heart (RPKM 403.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tomm6 in Genome Data Viewer
    Location:
    9q12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (20801806..20803174)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (13304269..13305637)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (15313346..15314872)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102554309 Neighboring gene progastricsin Neighboring gene fibroblast growth factor receptor substrate 3 Neighboring gene prickle planar cell polarity protein 4 Neighboring gene ubiquitin specific peptidase 49 Neighboring gene cAMP-dependent protein kinase inhibitor gamma-like Neighboring gene mediator complex subunit 20

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Biogenesis of mitochondrial outer membrane proteins, problems and diseases. Ellenrieder L, et al. Biol Chem, 2015 Nov. PMID 25980382
    2. Cooperation of protein machineries in mitochondrial protein sorting. Wenz LS, et al. Biochim Biophys Acta, 2015 May. PMID 25633533
    3. Assembly of β-barrel proteins in the mitochondrial outer membrane. Höhr AI, et al. Biochim Biophys Acta, 2015 Jan. PMID 25305573
    4. Unlocking the presequence import pathway. Schulz C, et al. Trends Cell Biol, 2015 May. PMID 25542066
    5. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial import receptor subunit TOM6 homolog
    Names
    prickle homolog 4
    translocase of outer mitochondrial membrane 6 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399365.1 → NP_001386294.1  mitochondrial import receptor subunit TOM6 homolog

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A6JII8
      Conserved Domains (1) summary
      pfam15184
      Location:1 → 74
      TOM6p; Mitochondrial import receptor subunit TOM6 homolog

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      20801806..20803174
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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