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    Zfp709l1 zinc finger protein 709-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690419, updated on 9-Dec-2024

    Summary

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    Symbol
    Zfp709l1provided by RGD
    Full Name
    zinc finger protein 709-like 1provided by RGD
    Primary source
    RGD:1596088
    See related
    EnsemblRapid:ENSRNOG00000067221 AllianceGenome:RGD:1596088
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF696 (zinc finger protein 696). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 103.2), Spleen (RPKM 94.5) and 9 other tissues See more
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    Genomic context

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    See Zfp709l1 in Genome Data Viewer
    Location:
    7q11
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (8328854..8359100, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (7683807..7708257, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (10412577..10436946, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene Syntaxin 8, pseudogene 1 Neighboring gene U2 spliceosomal RNA Neighboring gene zinc finger protein 709-like 3 Neighboring gene serine and arginine rich splicing factor 7, pseudogene 3 Neighboring gene U4 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons. Pintchovski SA, et al. J Neurosci, 2009 Feb 4. PMID 19193899, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arg3.1 in neurons is the first target of serum response factor and functions at synapses to mediate neuronal plasticity.
      Title: The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 878
    Names
    zinc finger protein 433-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163063.1 → NP_001156535.1  zinc finger protein 878

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A0A0G2K9M2
      Related
      ENSRNOP00000051405.5, ENSRNOT00000047433.5
      Conserved Domains (5) summary
      smart00349
      Location:4 → 47
      KRAB; krueppel associated box
      COG5048
      Location:144 → 497
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:276 → 296
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 43
      KRAB; KRAB box
      pfam13465
      Location:428 → 453
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      8328854..8359100 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008765131.4 → XP_008763353.1  zinc finger protein 878 isoform X2

      Conserved Domains (1) summary
      pfam01352
      Location:4 → 43
      KRAB; KRAB box

    2. XM_006240830.5 → XP_006240892.1  zinc finger protein 878 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZT66
      Conserved Domains (2) summary
      smart00349
      Location:4 → 47
      KRAB; krueppel associated box
      pfam01352
      Location:4 → 43
      KRAB; KRAB box

    RNA

    1. XR_001838721.3 RNA Sequence

    2. XR_001838720.3 RNA Sequence

    3. XR_355238.5 RNA Sequence

    4. XR_010053045.1 RNA Sequence

    5. XR_010053046.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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