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    Zfr2 zinc finger RNA binding protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314639, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfr2provided by RGD
    Official Full Name
    zinc finger RNA binding protein 2provided by RGD
    Primary source
    RGD:1304737
    See related
    EnsemblRapid:ENSRNOG00000020416 AllianceGenome:RGD:1304737
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1304737
    Summary
    Predicted to enable double-stranded RNA binding activity and single-stranded RNA binding activity. Predicted to be located in nucleus. Orthologous to human ZFR2 (zinc finger RNA binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 55.2), Adrenal (RPKM 37.5) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfr2 in Genome Data Viewer
    Location:
    7q11
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (9117490..9136315, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (8466768..8485593, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (11335024..11353743, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L54 Neighboring gene megakaryocyte-associated tyrosine kinase Neighboring gene ATCAY kinesin light chain interacting caytaxin Neighboring gene uncharacterized LOC134479805 Neighboring gene nicotinamide riboside kinase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables double-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables single-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger RNA-binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427319.1 → NP_001414248.1  zinc finger RNA-binding protein 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A0A8I5Y1D0
      Related
      ENSRNOP00000077260.2, ENSRNOT00000118230.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      9117490..9136315 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063263428.1 → XP_063119498.1  zinc finger RNA-binding protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8I5Y1D0, D4A148

    2. XM_039080435.2 → XP_038936363.1  zinc finger RNA-binding protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8I5Y1D0
      Conserved Domains (4) summary
      smart00451
      Location:136 → 163
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:138 → 184
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02675
      Location:519 → 770
      DZF; DZF domain
      pfam12874
      Location:333 → 357
      zf-met; Zinc-finger of C2H2 type

    3. XM_063263427.1 → XP_063119497.1  zinc finger RNA-binding protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I5Y1D0

    4. XM_006241033.5 → XP_006241095.1  zinc finger RNA-binding protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006241095.1

      UniProtKB/TrEMBL
      A0A8I5Y1D0
      Conserved Domains (3) summary
      smart00451
      Location:154 → 181
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:156 → 202
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02675
      Location:537 → 788
      DZF; DZF domain

    5. XM_039080436.2 → XP_038936364.1  zinc finger RNA-binding protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A8I5Y1D0
      Conserved Domains (4) summary
      smart00451
      Location:2 → 29
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:4 → 50
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02675
      Location:385 → 636
      DZF; DZF domain
      pfam12874
      Location:199 → 223
      zf-met; Zinc-finger of C2H2 type

    6. XM_039080438.2 → XP_038936366.1  zinc finger RNA-binding protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A8I5Y1D0
      Conserved Domains (5) summary
      smart00451
      Location:177 → 204
      ZnF_U1; U1-like zinc finger
      PHA03247
      Location:20 → 310
      PHA03247; large tegument protein UL36; Provisional
      sd00020
      Location:179 → 225
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02675
      Location:558 → 809
      DZF; DZF domain
      pfam12874
      Location:372 → 396
      zf-met; Zinc-finger of C2H2 type

    RNA

    1. XR_010052968.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials