U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Tmem250 transmembrane protein 250 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499758, updated on 27-Dec-2024

    Summary

    Official Symbol
    Tmem250provided by RGD
    Official Full Name
    transmembrane protein 250provided by RGD
    Primary source
    RGD:1564379
    See related
    EnsemblRapid:ENSRNOG00000042501 AllianceGenome:RGD:1564379
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564379
    Summary
    Predicted to be involved in positive regulation of cell population proliferation and positive regulation of viral process. Predicted to be located in cytoplasm and nucleoplasm. Orthologous to human TMEM250 (transmembrane protein 250). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 128.9), Heart (RPKM 104.3) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Tmem250 in Genome Data Viewer
    Location:
    3p13
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (29360770..29364756, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (8962657..8966349, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (3590783..3594475, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120101509 Neighboring gene NACC family member 2 Neighboring gene uncharacterized LOC103691752 Neighboring gene LIM homeobox 3 Neighboring gene quiescin sulfhydryl oxidase 2 Neighboring gene uncharacterized LOC120101510

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in positive regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of viral process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001126295.1NP_001119767.1  transmembrane protein 250

      See identical proteins and their annotated locations for NP_001119767.1

      Status: PROVISIONAL

      Source sequence(s)
      BC161868
      UniProtKB/TrEMBL
      B2GNF0
      Related
      ENSRNOP00000062164.1, ENSRNOT00000064861.3
      Conserved Domains (1) summary
      pfam17685
      Location:1139
      DUF5533; Family of unknown function (DUF5533)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      29360770..29364756 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006233691.4XP_006233753.1  transmembrane protein 250 isoform X1

      See identical proteins and their annotated locations for XP_006233753.1

      UniProtKB/TrEMBL
      B2GNF0
      Conserved Domains (1) summary
      pfam17685
      Location:1139
      DUF5533; Family of unknown function (DUF5533)
    2. XM_006233690.4XP_006233752.1  transmembrane protein 250 isoform X1

      See identical proteins and their annotated locations for XP_006233752.1

      UniProtKB/TrEMBL
      B2GNF0
      Conserved Domains (1) summary
      pfam17685
      Location:1139
      DUF5533; Family of unknown function (DUF5533)
    3. XM_006233692.2XP_006233754.1  transmembrane protein 250 isoform X1

      See identical proteins and their annotated locations for XP_006233754.1

      UniProtKB/TrEMBL
      B2GNF0
      Conserved Domains (1) summary
      pfam17685
      Location:1139
      DUF5533; Family of unknown function (DUF5533)