T24C12.3 Carbohydrate kinase PfkB domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: T24C12.3
Official Full Name: Carbohydrate kinase PfkB domain-containing protein
Primary source: WormBase:WBGene00020765
Locus tag: CELE_T24C12.3
See related: AllianceGenome:WB:WBGene00020765
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable pseudouridylate synthase activity. Predicted to be involved in phosphate-containing compound metabolic process and pseudouridine synthesis. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See T24C12.3 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 15

Sequence:: Chromosome: X; NC_003284.9 (2196525..2203893, complement)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003284.9

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Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T24C12.1 (e-PCR)
- UniSTS:315086

T24C12.4 (e-PCR)
- UniSTS:317154

T24C12.3 (e-PCR)
- UniSTS:305905

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables hydrolase activity, acting on glycosyl bonds	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables pseudouridylate synthase activity	IBA Inferred from Biological aspect of Ancestor more info
enables pseudouridylate synthase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in phosphate-containing compound metabolic process	IEA Inferred from Electronic Annotation more info
involved_in pseudouridine synthesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Carbohydrate kinase PfkB domain-containing protein

NP_508405.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

2196525..2203893 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_076004.8 → NP_508405.2 Carbohydrate kinase PfkB domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_508405.2

Status: REVIEWED

UniProtKB/TrEMBL

Q22721

Conserved Domains (2) summary

cd01941
Location:334 → 637

YeiC_kinase_like; YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.

pfam04227
Location:22 → 310

Indigoidine_A; Indigoidine synthase A like protein